Anti-Tumour Effect In Vitro of Lymphocytes and Macrophages from Mice Treated with Corynebacterium Parvum

Cells from the spleen, lymph node, peripheral blood and peritoneal exudate of mice treated with C. parvum were tested for their ability to inhibit tumour growth in vitro. The peritoneal exudate cells from C. parvum treated mice were extremely effective in inhibiting tumour growth whereas the spleen...

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Autores principales: Ghaffar, A., Cullen, R. T., Dunbar, N., Woodruff, M. F. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1974
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009103/
https://www.ncbi.nlm.nih.gov/pubmed/4830143
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author Ghaffar, A.
Cullen, R. T.
Dunbar, N.
Woodruff, M. F. A.
author_facet Ghaffar, A.
Cullen, R. T.
Dunbar, N.
Woodruff, M. F. A.
author_sort Ghaffar, A.
collection PubMed
description Cells from the spleen, lymph node, peripheral blood and peritoneal exudate of mice treated with C. parvum were tested for their ability to inhibit tumour growth in vitro. The peritoneal exudate cells from C. parvum treated mice were extremely effective in inhibiting tumour growth whereas the spleen and peripheral blood cells were only moderately so. In contrast, the lymph node cells caused only a modest inhibition of tumour growth at a very high effector to target cell ratio. Spleen cells from normal mice also exerted a moderate anti-tumour effect.
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spelling pubmed-20091032009-09-10 Anti-Tumour Effect In Vitro of Lymphocytes and Macrophages from Mice Treated with Corynebacterium Parvum Ghaffar, A. Cullen, R. T. Dunbar, N. Woodruff, M. F. A. Br J Cancer Articles Cells from the spleen, lymph node, peripheral blood and peritoneal exudate of mice treated with C. parvum were tested for their ability to inhibit tumour growth in vitro. The peritoneal exudate cells from C. parvum treated mice were extremely effective in inhibiting tumour growth whereas the spleen and peripheral blood cells were only moderately so. In contrast, the lymph node cells caused only a modest inhibition of tumour growth at a very high effector to target cell ratio. Spleen cells from normal mice also exerted a moderate anti-tumour effect. Nature Publishing Group 1974-03 /pmc/articles/PMC2009103/ /pubmed/4830143 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Ghaffar, A.
Cullen, R. T.
Dunbar, N.
Woodruff, M. F. A.
Anti-Tumour Effect In Vitro of Lymphocytes and Macrophages from Mice Treated with Corynebacterium Parvum
title Anti-Tumour Effect In Vitro of Lymphocytes and Macrophages from Mice Treated with Corynebacterium Parvum
title_full Anti-Tumour Effect In Vitro of Lymphocytes and Macrophages from Mice Treated with Corynebacterium Parvum
title_fullStr Anti-Tumour Effect In Vitro of Lymphocytes and Macrophages from Mice Treated with Corynebacterium Parvum
title_full_unstemmed Anti-Tumour Effect In Vitro of Lymphocytes and Macrophages from Mice Treated with Corynebacterium Parvum
title_short Anti-Tumour Effect In Vitro of Lymphocytes and Macrophages from Mice Treated with Corynebacterium Parvum
title_sort anti-tumour effect in vitro of lymphocytes and macrophages from mice treated with corynebacterium parvum
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009103/
https://www.ncbi.nlm.nih.gov/pubmed/4830143
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