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Reverse Transcriptase Activity: Increase in Marrow Cultures from Leukaemic Patients in Relapse and Remission

An enzyme activity with the characteristics of reverse transcriptase was detected in marrow from patients with leukaemia in relapse and in firm haematological remission. The endogenous enzyme activities increased following culture, and in remission patients the enzyme activities reached levels equal...

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Detalles Bibliográficos
Autores principales: Mak, T. W., Aye, M. T., Messner, H., Sheinin, R., Till, J. E., McCulloch, E. A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1974
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009110/
https://www.ncbi.nlm.nih.gov/pubmed/4137170
Descripción
Sumario:An enzyme activity with the characteristics of reverse transcriptase was detected in marrow from patients with leukaemia in relapse and in firm haematological remission. The endogenous enzyme activities increased following culture, and in remission patients the enzyme activities reached levels equal to or exceeding those found in relapse.