Differentiation Between the Embryonic and Tumour Specific Antigens on Chemically Induced Rat Tumours

The tumour specific antigens and tumour associated embryonic antigens expressed on chemically induced rat hepatomata and sarcomata have been shown to be different by means of blocking antibody studies. Serum from multiparous female rats contained blocking antibody which protected both tumour and emb...

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Detalles Bibliográficos
Autores principales: Baldwin, R. W., Glaves, D., Vose, B. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1974
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009139/
https://www.ncbi.nlm.nih.gov/pubmed/4362448
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author Baldwin, R. W.
Glaves, D.
Vose, B. M.
author_facet Baldwin, R. W.
Glaves, D.
Vose, B. M.
author_sort Baldwin, R. W.
collection PubMed
description The tumour specific antigens and tumour associated embryonic antigens expressed on chemically induced rat hepatomata and sarcomata have been shown to be different by means of blocking antibody studies. Serum from multiparous female rats contained blocking antibody which protected both tumour and embryo cells from the in vitro cytotoxic effect of lymph node cells from multiparous donors. These sera did not, however, block the cytotoxicity of lymph node cells from tumour immune rats for cells of the immunizing tumour. In addition, the tumour specific rejection antigens and embryonic antigens have been shown to have dissimilar locations in tumour cells.
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spelling pubmed-20091392009-09-10 Differentiation Between the Embryonic and Tumour Specific Antigens on Chemically Induced Rat Tumours Baldwin, R. W. Glaves, D. Vose, B. M. Br J Cancer Articles The tumour specific antigens and tumour associated embryonic antigens expressed on chemically induced rat hepatomata and sarcomata have been shown to be different by means of blocking antibody studies. Serum from multiparous female rats contained blocking antibody which protected both tumour and embryo cells from the in vitro cytotoxic effect of lymph node cells from multiparous donors. These sera did not, however, block the cytotoxicity of lymph node cells from tumour immune rats for cells of the immunizing tumour. In addition, the tumour specific rejection antigens and embryonic antigens have been shown to have dissimilar locations in tumour cells. Nature Publishing Group 1974-01 /pmc/articles/PMC2009139/ /pubmed/4362448 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Baldwin, R. W.
Glaves, D.
Vose, B. M.
Differentiation Between the Embryonic and Tumour Specific Antigens on Chemically Induced Rat Tumours
title Differentiation Between the Embryonic and Tumour Specific Antigens on Chemically Induced Rat Tumours
title_full Differentiation Between the Embryonic and Tumour Specific Antigens on Chemically Induced Rat Tumours
title_fullStr Differentiation Between the Embryonic and Tumour Specific Antigens on Chemically Induced Rat Tumours
title_full_unstemmed Differentiation Between the Embryonic and Tumour Specific Antigens on Chemically Induced Rat Tumours
title_short Differentiation Between the Embryonic and Tumour Specific Antigens on Chemically Induced Rat Tumours
title_sort differentiation between the embryonic and tumour specific antigens on chemically induced rat tumours
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009139/
https://www.ncbi.nlm.nih.gov/pubmed/4362448
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AT glavesd differentiationbetweentheembryonicandtumourspecificantigensonchemicallyinducedrattumours
AT vosebm differentiationbetweentheembryonicandtumourspecificantigensonchemicallyinducedrattumours

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