Cellular Immunity, Peripheral Blood Lymphocyte Count and Pathological Staging of Tumours in the Gastrointestinal Tract

The peripheral blood lymphocyte count has been measured in 74 cases of histologically proven carcinoma of the gastrointestinal tract. The count has been correlated with the pathological stage of tumour spread and the patient's delayed hypersensitivity response to 2.4 dinitrochlorobenzene (DNCB)...

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Detalles Bibliográficos
Autores principales: Bone, G., Lauder, I.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1974
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009205/
https://www.ncbi.nlm.nih.gov/pubmed/4451626
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author Bone, G.
Lauder, I.
author_facet Bone, G.
Lauder, I.
author_sort Bone, G.
collection PubMed
description The peripheral blood lymphocyte count has been measured in 74 cases of histologically proven carcinoma of the gastrointestinal tract. The count has been correlated with the pathological stage of tumour spread and the patient's delayed hypersensitivity response to 2.4 dinitrochlorobenzene (DNCB). A statistically significant correlation was found between the peripheral blood lymphocyte count and the response to DNCB. There was linear association between the extent of spread of the tumours and the lymphocyte count. Those patients with low peripheral blood lymphocyte counts tended to have more advanced tumours and a poor response to DNCB. The possible causes of this lymphopenia are discussed.
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spelling pubmed-20092052009-09-10 Cellular Immunity, Peripheral Blood Lymphocyte Count and Pathological Staging of Tumours in the Gastrointestinal Tract Bone, G. Lauder, I. Br J Cancer Articles The peripheral blood lymphocyte count has been measured in 74 cases of histologically proven carcinoma of the gastrointestinal tract. The count has been correlated with the pathological stage of tumour spread and the patient's delayed hypersensitivity response to 2.4 dinitrochlorobenzene (DNCB). A statistically significant correlation was found between the peripheral blood lymphocyte count and the response to DNCB. There was linear association between the extent of spread of the tumours and the lymphocyte count. Those patients with low peripheral blood lymphocyte counts tended to have more advanced tumours and a poor response to DNCB. The possible causes of this lymphopenia are discussed. Nature Publishing Group 1974-09 /pmc/articles/PMC2009205/ /pubmed/4451626 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Bone, G.
Lauder, I.
Cellular Immunity, Peripheral Blood Lymphocyte Count and Pathological Staging of Tumours in the Gastrointestinal Tract
title Cellular Immunity, Peripheral Blood Lymphocyte Count and Pathological Staging of Tumours in the Gastrointestinal Tract
title_full Cellular Immunity, Peripheral Blood Lymphocyte Count and Pathological Staging of Tumours in the Gastrointestinal Tract
title_fullStr Cellular Immunity, Peripheral Blood Lymphocyte Count and Pathological Staging of Tumours in the Gastrointestinal Tract
title_full_unstemmed Cellular Immunity, Peripheral Blood Lymphocyte Count and Pathological Staging of Tumours in the Gastrointestinal Tract
title_short Cellular Immunity, Peripheral Blood Lymphocyte Count and Pathological Staging of Tumours in the Gastrointestinal Tract
title_sort cellular immunity, peripheral blood lymphocyte count and pathological staging of tumours in the gastrointestinal tract
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009205/
https://www.ncbi.nlm.nih.gov/pubmed/4451626
work_keys_str_mv AT boneg cellularimmunityperipheralbloodlymphocytecountandpathologicalstagingoftumoursinthegastrointestinaltract
AT lauderi cellularimmunityperipheralbloodlymphocytecountandpathologicalstagingoftumoursinthegastrointestinaltract

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