Embryonic Antigen Expression on 2-Acetylaminofluorene Induced and Spontaneously Arising Rat Tumours

2-Acetylaminofluorene induced mammary and ear duct carcinomata and spontaneously arising mammary carcinomata and sarcomata were shown to express embryonic antigens at the cell surface by their reaction with serum from multiparous female rats. These observations with essentially non-immunogenic tumou...

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Detalles Bibliográficos
Autores principales: Baldwin, R. W., Vose, B. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1974
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009207/
https://www.ncbi.nlm.nih.gov/pubmed/4615731
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author Baldwin, R. W.
Vose, B. M.
author_facet Baldwin, R. W.
Vose, B. M.
author_sort Baldwin, R. W.
collection PubMed
description 2-Acetylaminofluorene induced mammary and ear duct carcinomata and spontaneously arising mammary carcinomata and sarcomata were shown to express embryonic antigens at the cell surface by their reaction with serum from multiparous female rats. These observations with essentially non-immunogenic tumours are comparable with early findings showing that embryonic antigens are also expressed on aminoazo dye induced rat hepatomata, and sarcomata induced with 3-methylcholanthrene. Re-expression of embryonal components, therefore, may be a concomitant of neoplastic transformation.
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spelling pubmed-20092072009-09-10 Embryonic Antigen Expression on 2-Acetylaminofluorene Induced and Spontaneously Arising Rat Tumours Baldwin, R. W. Vose, B. M. Br J Cancer Articles 2-Acetylaminofluorene induced mammary and ear duct carcinomata and spontaneously arising mammary carcinomata and sarcomata were shown to express embryonic antigens at the cell surface by their reaction with serum from multiparous female rats. These observations with essentially non-immunogenic tumours are comparable with early findings showing that embryonic antigens are also expressed on aminoazo dye induced rat hepatomata, and sarcomata induced with 3-methylcholanthrene. Re-expression of embryonal components, therefore, may be a concomitant of neoplastic transformation. Nature Publishing Group 1974-09 /pmc/articles/PMC2009207/ /pubmed/4615731 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Baldwin, R. W.
Vose, B. M.
Embryonic Antigen Expression on 2-Acetylaminofluorene Induced and Spontaneously Arising Rat Tumours
title Embryonic Antigen Expression on 2-Acetylaminofluorene Induced and Spontaneously Arising Rat Tumours
title_full Embryonic Antigen Expression on 2-Acetylaminofluorene Induced and Spontaneously Arising Rat Tumours
title_fullStr Embryonic Antigen Expression on 2-Acetylaminofluorene Induced and Spontaneously Arising Rat Tumours
title_full_unstemmed Embryonic Antigen Expression on 2-Acetylaminofluorene Induced and Spontaneously Arising Rat Tumours
title_short Embryonic Antigen Expression on 2-Acetylaminofluorene Induced and Spontaneously Arising Rat Tumours
title_sort embryonic antigen expression on 2-acetylaminofluorene induced and spontaneously arising rat tumours
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009207/
https://www.ncbi.nlm.nih.gov/pubmed/4615731
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