Ascorbic Acid Deficiency in Malignant Diseases: A Clinical and Biochemical Study

In a study of the vitamin C status of 50 patients with malignant disease, 46 had leucocyte levels less than the lower limit of the normal range (18-50,μg/10(8) W.B.C.) and of these 30 had very low levels (< 12.5 μg/10(8) W.B.C.). Physical signs compatible with subclinical scurvy were frequently r...

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Detalles Bibliográficos
Autores principales: Krasner, N., Dymock, I. W.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1974
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009278/
https://www.ncbi.nlm.nih.gov/pubmed/4423667
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author Krasner, N.
Dymock, I. W.
author_facet Krasner, N.
Dymock, I. W.
author_sort Krasner, N.
collection PubMed
description In a study of the vitamin C status of 50 patients with malignant disease, 46 had leucocyte levels less than the lower limit of the normal range (18-50,μg/10(8) W.B.C.) and of these 30 had very low levels (< 12.5 μg/10(8) W.B.C.). Physical signs compatible with subclinical scurvy were frequently recorded and there was a significant decrease in capillary fragility in those with the lowest levels. Most patients had an inadequate dietary intake of ascorbic acid-containing foods and this was felt to be the major factor in producing the vitamin depletion.
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spelling pubmed-20092782009-09-10 Ascorbic Acid Deficiency in Malignant Diseases: A Clinical and Biochemical Study Krasner, N. Dymock, I. W. Br J Cancer Articles In a study of the vitamin C status of 50 patients with malignant disease, 46 had leucocyte levels less than the lower limit of the normal range (18-50,μg/10(8) W.B.C.) and of these 30 had very low levels (< 12.5 μg/10(8) W.B.C.). Physical signs compatible with subclinical scurvy were frequently recorded and there was a significant decrease in capillary fragility in those with the lowest levels. Most patients had an inadequate dietary intake of ascorbic acid-containing foods and this was felt to be the major factor in producing the vitamin depletion. Nature Publishing Group 1974-08 /pmc/articles/PMC2009278/ /pubmed/4423667 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Krasner, N.
Dymock, I. W.
Ascorbic Acid Deficiency in Malignant Diseases: A Clinical and Biochemical Study
title Ascorbic Acid Deficiency in Malignant Diseases: A Clinical and Biochemical Study
title_full Ascorbic Acid Deficiency in Malignant Diseases: A Clinical and Biochemical Study
title_fullStr Ascorbic Acid Deficiency in Malignant Diseases: A Clinical and Biochemical Study
title_full_unstemmed Ascorbic Acid Deficiency in Malignant Diseases: A Clinical and Biochemical Study
title_short Ascorbic Acid Deficiency in Malignant Diseases: A Clinical and Biochemical Study
title_sort ascorbic acid deficiency in malignant diseases: a clinical and biochemical study
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009278/
https://www.ncbi.nlm.nih.gov/pubmed/4423667
work_keys_str_mv AT krasnern ascorbicaciddeficiencyinmalignantdiseasesaclinicalandbiochemicalstudy
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