Combination of Carcinoembryonic Antigen and Gamma Glutamyl Transpeptidase in the Study of The Evolution of Colorectal Cancer

Plasma CEA values and serum γ glutamyl transpeptidase activities have been compared in control subjects and 109 patients with colorectal carcinoma and 35 with non-malignant hepatic disease. CEA values alone differentiate hepatic metastases from non-malignant hepatic disease with a high degree of cer...

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Autores principales: Steele, L., Cooper, E. H., Mackay, A. M., Losowsky, M. S., Goligher, J. C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1974
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009290/
https://www.ncbi.nlm.nih.gov/pubmed/4155643
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author Steele, L.
Cooper, E. H.
Mackay, A. M.
Losowsky, M. S.
Goligher, J. C.
author_facet Steele, L.
Cooper, E. H.
Mackay, A. M.
Losowsky, M. S.
Goligher, J. C.
author_sort Steele, L.
collection PubMed
description Plasma CEA values and serum γ glutamyl transpeptidase activities have been compared in control subjects and 109 patients with colorectal carcinoma and 35 with non-malignant hepatic disease. CEA values alone differentiate hepatic metastases from non-malignant hepatic disease with a high degree of certainty. While CEA may be elevated with metastases, irrespective of site, γGT is elevated mainly in association with hepatic metastases. The combination of CEA and γGT is helpful in identifying hepatic metastases and in their differentiation from local recurrences or metastases to other sites.
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spelling pubmed-20092902009-09-10 Combination of Carcinoembryonic Antigen and Gamma Glutamyl Transpeptidase in the Study of The Evolution of Colorectal Cancer Steele, L. Cooper, E. H. Mackay, A. M. Losowsky, M. S. Goligher, J. C. Br J Cancer Articles Plasma CEA values and serum γ glutamyl transpeptidase activities have been compared in control subjects and 109 patients with colorectal carcinoma and 35 with non-malignant hepatic disease. CEA values alone differentiate hepatic metastases from non-malignant hepatic disease with a high degree of certainty. While CEA may be elevated with metastases, irrespective of site, γGT is elevated mainly in association with hepatic metastases. The combination of CEA and γGT is helpful in identifying hepatic metastases and in their differentiation from local recurrences or metastases to other sites. Nature Publishing Group 1974-10 /pmc/articles/PMC2009290/ /pubmed/4155643 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Steele, L.
Cooper, E. H.
Mackay, A. M.
Losowsky, M. S.
Goligher, J. C.
Combination of Carcinoembryonic Antigen and Gamma Glutamyl Transpeptidase in the Study of The Evolution of Colorectal Cancer
title Combination of Carcinoembryonic Antigen and Gamma Glutamyl Transpeptidase in the Study of The Evolution of Colorectal Cancer
title_full Combination of Carcinoembryonic Antigen and Gamma Glutamyl Transpeptidase in the Study of The Evolution of Colorectal Cancer
title_fullStr Combination of Carcinoembryonic Antigen and Gamma Glutamyl Transpeptidase in the Study of The Evolution of Colorectal Cancer
title_full_unstemmed Combination of Carcinoembryonic Antigen and Gamma Glutamyl Transpeptidase in the Study of The Evolution of Colorectal Cancer
title_short Combination of Carcinoembryonic Antigen and Gamma Glutamyl Transpeptidase in the Study of The Evolution of Colorectal Cancer
title_sort combination of carcinoembryonic antigen and gamma glutamyl transpeptidase in the study of the evolution of colorectal cancer
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009290/
https://www.ncbi.nlm.nih.gov/pubmed/4155643
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