Tumour Colony Growth in the Irradiated Mouse Lung

The effect of irradiation of recipient mouse lung on tumour colony growth after intravenous injection of C3H mammary adenocarcinoma cells or aggregates was tested in C3H male mice irradiated with 14 MeV electrons to the whole or half of the thorax. Injections were made 3 h, 48 h, 3½ months or 9½ mon...

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Detalles Bibliográficos
Autor principal: Thompson, S. C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1974
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009291/
https://www.ncbi.nlm.nih.gov/pubmed/4447776
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author Thompson, S. C.
author_facet Thompson, S. C.
author_sort Thompson, S. C.
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description The effect of irradiation of recipient mouse lung on tumour colony growth after intravenous injection of C3H mammary adenocarcinoma cells or aggregates was tested in C3H male mice irradiated with 14 MeV electrons to the whole or half of the thorax. Injections were made 3 h, 48 h, 3½ months or 9½ months after irradiation. The number and size of colonies were increased in irradiated areas of the lung at 48 h and at 3½ months after doses of 2000 rad. However, 9½ months after irradiation lungs were found to be atrophied and fibrotic and enumeration of tumour colonies was found to be impossible. An increase in colony growth after 250 rad was seen only at 9½ months after irradiation. IMAGES:
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spelling pubmed-20092912009-09-10 Tumour Colony Growth in the Irradiated Mouse Lung Thompson, S. C. Br J Cancer Articles The effect of irradiation of recipient mouse lung on tumour colony growth after intravenous injection of C3H mammary adenocarcinoma cells or aggregates was tested in C3H male mice irradiated with 14 MeV electrons to the whole or half of the thorax. Injections were made 3 h, 48 h, 3½ months or 9½ months after irradiation. The number and size of colonies were increased in irradiated areas of the lung at 48 h and at 3½ months after doses of 2000 rad. However, 9½ months after irradiation lungs were found to be atrophied and fibrotic and enumeration of tumour colonies was found to be impossible. An increase in colony growth after 250 rad was seen only at 9½ months after irradiation. IMAGES: Nature Publishing Group 1974-10 /pmc/articles/PMC2009291/ /pubmed/4447776 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Thompson, S. C.
Tumour Colony Growth in the Irradiated Mouse Lung
title Tumour Colony Growth in the Irradiated Mouse Lung
title_full Tumour Colony Growth in the Irradiated Mouse Lung
title_fullStr Tumour Colony Growth in the Irradiated Mouse Lung
title_full_unstemmed Tumour Colony Growth in the Irradiated Mouse Lung
title_short Tumour Colony Growth in the Irradiated Mouse Lung
title_sort tumour colony growth in the irradiated mouse lung
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009291/
https://www.ncbi.nlm.nih.gov/pubmed/4447776
work_keys_str_mv AT thompsonsc tumourcolonygrowthintheirradiatedmouselung

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