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The Effect of Irradiating a Transplanted Solid Sarcoma on the Subsequent Development of Metastases
A slowly growing solid sarcoma was implanted subcutaneously on the anterior chest wall of mice. On reaching a predetermined size the tumours were locally irradiated using 240 kV x-rays with single doses of 0, 2000 or 5000 rad. The mice were sacrificed 12 weeks after irradiation and examined for lung...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1974
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009314/ https://www.ncbi.nlm.nih.gov/pubmed/4469194 |
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author | Sheldon, P. W. |
author_facet | Sheldon, P. W. |
author_sort | Sheldon, P. W. |
collection | PubMed |
description | A slowly growing solid sarcoma was implanted subcutaneously on the anterior chest wall of mice. On reaching a predetermined size the tumours were locally irradiated using 240 kV x-rays with single doses of 0, 2000 or 5000 rad. The mice were sacrificed 12 weeks after irradiation and examined for lung metastases, which were found to be less frequent in those mice whose implanted tumours had received the most irradiation. |
format | Text |
id | pubmed-2009314 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1974 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20093142009-09-10 The Effect of Irradiating a Transplanted Solid Sarcoma on the Subsequent Development of Metastases Sheldon, P. W. Br J Cancer Articles A slowly growing solid sarcoma was implanted subcutaneously on the anterior chest wall of mice. On reaching a predetermined size the tumours were locally irradiated using 240 kV x-rays with single doses of 0, 2000 or 5000 rad. The mice were sacrificed 12 weeks after irradiation and examined for lung metastases, which were found to be less frequent in those mice whose implanted tumours had received the most irradiation. Nature Publishing Group 1974-11 /pmc/articles/PMC2009314/ /pubmed/4469194 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Articles Sheldon, P. W. The Effect of Irradiating a Transplanted Solid Sarcoma on the Subsequent Development of Metastases |
title | The Effect of Irradiating a Transplanted Solid Sarcoma on the Subsequent Development of Metastases |
title_full | The Effect of Irradiating a Transplanted Solid Sarcoma on the Subsequent Development of Metastases |
title_fullStr | The Effect of Irradiating a Transplanted Solid Sarcoma on the Subsequent Development of Metastases |
title_full_unstemmed | The Effect of Irradiating a Transplanted Solid Sarcoma on the Subsequent Development of Metastases |
title_short | The Effect of Irradiating a Transplanted Solid Sarcoma on the Subsequent Development of Metastases |
title_sort | effect of irradiating a transplanted solid sarcoma on the subsequent development of metastases |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009314/ https://www.ncbi.nlm.nih.gov/pubmed/4469194 |
work_keys_str_mv | AT sheldonpw theeffectofirradiatingatransplantedsolidsarcomaonthesubsequentdevelopmentofmetastases AT sheldonpw effectofirradiatingatransplantedsolidsarcomaonthesubsequentdevelopmentofmetastases |