Radiological Detection and Sequential Observation of Experimentally Induced Bladder Tumours in the European Hamster

Four groups of European hamsters (strain MHH: EPH) were treated subcutaneously once weekly for life with 1/20 or 1/40 the LD(50) of DBN while another 2 groups served as controls. Three animals of each group were x-rayed every 2 weeks after i.v. injection of the contrast agent Urographin. By means of...

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Autores principales: Eckel, H., Reznik, G., Reznik-Schüller, H., Ohse, B., Mohr, U.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1974
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009331/
https://www.ncbi.nlm.nih.gov/pubmed/4447782
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author Eckel, H.
Reznik, G.
Reznik-Schüller, H.
Ohse, B.
Mohr, U.
author_facet Eckel, H.
Reznik, G.
Reznik-Schüller, H.
Ohse, B.
Mohr, U.
author_sort Eckel, H.
collection PubMed
description Four groups of European hamsters (strain MHH: EPH) were treated subcutaneously once weekly for life with 1/20 or 1/40 the LD(50) of DBN while another 2 groups served as controls. Three animals of each group were x-rayed every 2 weeks after i.v. injection of the contrast agent Urographin. By means of cystograms tumours of the urinary bladder were detected between the 20th and 26th weeks after beginning treatment when they had reached a diameter of 1-2 mm; their development was subsequently observed by periodical x-ray examinations. The technique described is simple and provides a valuable means for obtaining additional in vivo information concerning latency period, growth rate and identity of experimentally induced primary urinary bladder tumours in the European hamster. IMAGES:
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spelling pubmed-20093312009-09-10 Radiological Detection and Sequential Observation of Experimentally Induced Bladder Tumours in the European Hamster Eckel, H. Reznik, G. Reznik-Schüller, H. Ohse, B. Mohr, U. Br J Cancer Articles Four groups of European hamsters (strain MHH: EPH) were treated subcutaneously once weekly for life with 1/20 or 1/40 the LD(50) of DBN while another 2 groups served as controls. Three animals of each group were x-rayed every 2 weeks after i.v. injection of the contrast agent Urographin. By means of cystograms tumours of the urinary bladder were detected between the 20th and 26th weeks after beginning treatment when they had reached a diameter of 1-2 mm; their development was subsequently observed by periodical x-ray examinations. The technique described is simple and provides a valuable means for obtaining additional in vivo information concerning latency period, growth rate and identity of experimentally induced primary urinary bladder tumours in the European hamster. IMAGES: Nature Publishing Group 1974-12 /pmc/articles/PMC2009331/ /pubmed/4447782 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Articles
Eckel, H.
Reznik, G.
Reznik-Schüller, H.
Ohse, B.
Mohr, U.
Radiological Detection and Sequential Observation of Experimentally Induced Bladder Tumours in the European Hamster
title Radiological Detection and Sequential Observation of Experimentally Induced Bladder Tumours in the European Hamster
title_full Radiological Detection and Sequential Observation of Experimentally Induced Bladder Tumours in the European Hamster
title_fullStr Radiological Detection and Sequential Observation of Experimentally Induced Bladder Tumours in the European Hamster
title_full_unstemmed Radiological Detection and Sequential Observation of Experimentally Induced Bladder Tumours in the European Hamster
title_short Radiological Detection and Sequential Observation of Experimentally Induced Bladder Tumours in the European Hamster
title_sort radiological detection and sequential observation of experimentally induced bladder tumours in the european hamster
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009331/
https://www.ncbi.nlm.nih.gov/pubmed/4447782
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