The contribution of serum enzymes and carcinoembryonic antigen to the early diagnosis of metastatic colorectal cancer.

The evolution of metastatic colorectal cancer in patients who have had surgical treatment for a primary lesion was studied in relation the progressive changes in the blood levels of carcinembryonic antigen (CEA), to gamma glutamyl transpeptidase (GGT) and routine liver function tests (LFTs). Involve...

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Autores principales: Cooper, E. H., Turner, R., Steele, L., Neville, A. M., Mackay, A. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1975
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009361/
https://www.ncbi.nlm.nih.gov/pubmed/239735
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author Cooper, E. H.
Turner, R.
Steele, L.
Neville, A. M.
Mackay, A. M.
author_facet Cooper, E. H.
Turner, R.
Steele, L.
Neville, A. M.
Mackay, A. M.
author_sort Cooper, E. H.
collection PubMed
description The evolution of metastatic colorectal cancer in patients who have had surgical treatment for a primary lesion was studied in relation the progressive changes in the blood levels of carcinembryonic antigen (CEA), to gamma glutamyl transpeptidase (GGT) and routine liver function tests (LFTs). Involvement of the liver could ofter be reliably predicted many weeks in advance of clinical diagnosis while metastases to other sites were less likely to be detected early by this test. The association of the extent of disease with the patterns of biochemical changes is discussed with reference to several illustrative examples.
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spelling pubmed-20093612009-09-10 The contribution of serum enzymes and carcinoembryonic antigen to the early diagnosis of metastatic colorectal cancer. Cooper, E. H. Turner, R. Steele, L. Neville, A. M. Mackay, A. M. Br J Cancer Research Article The evolution of metastatic colorectal cancer in patients who have had surgical treatment for a primary lesion was studied in relation the progressive changes in the blood levels of carcinembryonic antigen (CEA), to gamma glutamyl transpeptidase (GGT) and routine liver function tests (LFTs). Involvement of the liver could ofter be reliably predicted many weeks in advance of clinical diagnosis while metastases to other sites were less likely to be detected early by this test. The association of the extent of disease with the patterns of biochemical changes is discussed with reference to several illustrative examples. Nature Publishing Group 1975-01 /pmc/articles/PMC2009361/ /pubmed/239735 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Cooper, E. H.
Turner, R.
Steele, L.
Neville, A. M.
Mackay, A. M.
The contribution of serum enzymes and carcinoembryonic antigen to the early diagnosis of metastatic colorectal cancer.
title The contribution of serum enzymes and carcinoembryonic antigen to the early diagnosis of metastatic colorectal cancer.
title_full The contribution of serum enzymes and carcinoembryonic antigen to the early diagnosis of metastatic colorectal cancer.
title_fullStr The contribution of serum enzymes and carcinoembryonic antigen to the early diagnosis of metastatic colorectal cancer.
title_full_unstemmed The contribution of serum enzymes and carcinoembryonic antigen to the early diagnosis of metastatic colorectal cancer.
title_short The contribution of serum enzymes and carcinoembryonic antigen to the early diagnosis of metastatic colorectal cancer.
title_sort contribution of serum enzymes and carcinoembryonic antigen to the early diagnosis of metastatic colorectal cancer.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009361/
https://www.ncbi.nlm.nih.gov/pubmed/239735
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