Study of the antigenic cross reactivity between carcinoembryonic antigen and "nonspecific cross reacting antigens" (NCA and NCA 2).

The immunochemical relationship between CEA, NCA and NCA 2 was studied in guinea-pigs. Strong cross reactions were found between these antigens, either in delayed or anaphylactic reactions. Some specific determinants for each antigen could still be demonstrated. Delayed hypersensitivity is likely to...

Descripción completa

Detalles Bibliográficos
Autores principales: Neveu, T., Staebler, D., Chavanel, G., Burtin, P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1975
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009431/
https://www.ncbi.nlm.nih.gov/pubmed/50854
_version_ 1782136114175279104
author Neveu, T.
Staebler, D.
Chavanel, G.
Burtin, P.
author_facet Neveu, T.
Staebler, D.
Chavanel, G.
Burtin, P.
author_sort Neveu, T.
collection PubMed
description The immunochemical relationship between CEA, NCA and NCA 2 was studied in guinea-pigs. Strong cross reactions were found between these antigens, either in delayed or anaphylactic reactions. Some specific determinants for each antigen could still be demonstrated. Delayed hypersensitivity is likely to be due to the protein moiety of the molecules while anaphylactic reactivity could probably be related to their glucidic parts. Consequently, CEA and NCA have common antigenic determinants on their glucidic and peptidic moieties, perhaps more on the latter ones.
format Text
id pubmed-2009431
institution National Center for Biotechnology Information
language English
publishDate 1975
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20094312009-09-10 Study of the antigenic cross reactivity between carcinoembryonic antigen and "nonspecific cross reacting antigens" (NCA and NCA 2). Neveu, T. Staebler, D. Chavanel, G. Burtin, P. Br J Cancer Research Article The immunochemical relationship between CEA, NCA and NCA 2 was studied in guinea-pigs. Strong cross reactions were found between these antigens, either in delayed or anaphylactic reactions. Some specific determinants for each antigen could still be demonstrated. Delayed hypersensitivity is likely to be due to the protein moiety of the molecules while anaphylactic reactivity could probably be related to their glucidic parts. Consequently, CEA and NCA have common antigenic determinants on their glucidic and peptidic moieties, perhaps more on the latter ones. Nature Publishing Group 1975-05 /pmc/articles/PMC2009431/ /pubmed/50854 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Neveu, T.
Staebler, D.
Chavanel, G.
Burtin, P.
Study of the antigenic cross reactivity between carcinoembryonic antigen and "nonspecific cross reacting antigens" (NCA and NCA 2).
title Study of the antigenic cross reactivity between carcinoembryonic antigen and "nonspecific cross reacting antigens" (NCA and NCA 2).
title_full Study of the antigenic cross reactivity between carcinoembryonic antigen and "nonspecific cross reacting antigens" (NCA and NCA 2).
title_fullStr Study of the antigenic cross reactivity between carcinoembryonic antigen and "nonspecific cross reacting antigens" (NCA and NCA 2).
title_full_unstemmed Study of the antigenic cross reactivity between carcinoembryonic antigen and "nonspecific cross reacting antigens" (NCA and NCA 2).
title_short Study of the antigenic cross reactivity between carcinoembryonic antigen and "nonspecific cross reacting antigens" (NCA and NCA 2).
title_sort study of the antigenic cross reactivity between carcinoembryonic antigen and "nonspecific cross reacting antigens" (nca and nca 2).
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009431/
https://www.ncbi.nlm.nih.gov/pubmed/50854
work_keys_str_mv AT neveut studyoftheantigeniccrossreactivitybetweencarcinoembryonicantigenandnonspecificcrossreactingantigensncaandnca2
AT staeblerd studyoftheantigeniccrossreactivitybetweencarcinoembryonicantigenandnonspecificcrossreactingantigensncaandnca2
AT chavanelg studyoftheantigeniccrossreactivitybetweencarcinoembryonicantigenandnonspecificcrossreactingantigensncaandnca2
AT burtinp studyoftheantigeniccrossreactivitybetweencarcinoembryonicantigenandnonspecificcrossreactingantigensncaandnca2

Ejemplares similares