Response of rat lung to 3,4-benzpyrene administered by intratracheal instillation in infusine with or without carbon black.

In a controlled experiment groups of SPF Wistar rats were give 18 once-fortnightly doses of 0-5, 1-0 or 2-0 mg 3,4-benzpyrene (BP) suspended in infusine (I) or in carbon black (CB) + I by intratracheal instillation. Of rats examined post mortem, 1/16 given I+CB only, 0/16 given I only, 15/51 given B...

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Detalles Bibliográficos
Autores principales: Davis, B. R., Whitehead, J. K., Gill, M. E., Lee, P. N., Butterworth, A. D., Roe, F. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1975
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009456/
https://www.ncbi.nlm.nih.gov/pubmed/1156525

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