Cargando…
Biosynthesis of 17beta-oestradiol in human breast carcinoma tissue and a novel method for its characterization.
Conversion of 7alpha3H-testosterone to 17beta-oestradiol by human mammary carcinoma tissue in vitro has been demonstrated. It was characterized unequivocally by conversion to 17beta-oestradiol-3-sulphate upon incubation with adenosine-3'-phosphate-5'-phosphosulphate and the highly specific...
Autores principales: | , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1975
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009460/ https://www.ncbi.nlm.nih.gov/pubmed/1156524 |
_version_ | 1782136119598514176 |
---|---|
author | Adams, J. B. Li, K. |
author_facet | Adams, J. B. Li, K. |
author_sort | Adams, J. B. |
collection | PubMed |
description | Conversion of 7alpha3H-testosterone to 17beta-oestradiol by human mammary carcinoma tissue in vitro has been demonstrated. It was characterized unequivocally by conversion to 17beta-oestradiol-3-sulphate upon incubation with adenosine-3'-phosphate-5'-phosphosulphate and the highly specific enzyme oestrogen sulphotransferase. |
format | Text |
id | pubmed-2009460 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1975 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20094602009-09-10 Biosynthesis of 17beta-oestradiol in human breast carcinoma tissue and a novel method for its characterization. Adams, J. B. Li, K. Br J Cancer Research Article Conversion of 7alpha3H-testosterone to 17beta-oestradiol by human mammary carcinoma tissue in vitro has been demonstrated. It was characterized unequivocally by conversion to 17beta-oestradiol-3-sulphate upon incubation with adenosine-3'-phosphate-5'-phosphosulphate and the highly specific enzyme oestrogen sulphotransferase. Nature Publishing Group 1975-04 /pmc/articles/PMC2009460/ /pubmed/1156524 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Adams, J. B. Li, K. Biosynthesis of 17beta-oestradiol in human breast carcinoma tissue and a novel method for its characterization. |
title | Biosynthesis of 17beta-oestradiol in human breast carcinoma tissue and a novel method for its characterization. |
title_full | Biosynthesis of 17beta-oestradiol in human breast carcinoma tissue and a novel method for its characterization. |
title_fullStr | Biosynthesis of 17beta-oestradiol in human breast carcinoma tissue and a novel method for its characterization. |
title_full_unstemmed | Biosynthesis of 17beta-oestradiol in human breast carcinoma tissue and a novel method for its characterization. |
title_short | Biosynthesis of 17beta-oestradiol in human breast carcinoma tissue and a novel method for its characterization. |
title_sort | biosynthesis of 17beta-oestradiol in human breast carcinoma tissue and a novel method for its characterization. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009460/ https://www.ncbi.nlm.nih.gov/pubmed/1156524 |
work_keys_str_mv | AT adamsjb biosynthesisof17betaoestradiolinhumanbreastcarcinomatissueandanovelmethodforitscharacterization AT lik biosynthesisof17betaoestradiolinhumanbreastcarcinomatissueandanovelmethodforitscharacterization |