Immunoadherence and complement in cancer-bearing mice.

Shortly after grafting of Ehrlich ascites carcinoma cells, the serum of tumour-bearing mice loses the capacity to mediate immunoadherence phenomena, because of a sharp decrease in the concentration of C3b and C3d, while the cellular receptors for such factors are unaffected by tumour growth. It is s...

Descripción completa

Detalles Bibliográficos
Autores principales: Porta, C., Villa, M. L., Clerici, E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1978
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009489/
https://www.ncbi.nlm.nih.gov/pubmed/619956
_version_ 1782136125081518080
author Porta, C.
Villa, M. L.
Clerici, E.
author_facet Porta, C.
Villa, M. L.
Clerici, E.
author_sort Porta, C.
collection PubMed
description Shortly after grafting of Ehrlich ascites carcinoma cells, the serum of tumour-bearing mice loses the capacity to mediate immunoadherence phenomena, because of a sharp decrease in the concentration of C3b and C3d, while the cellular receptors for such factors are unaffected by tumour growth. It is suggested that complement is consumed through the alternative pathway which is activated during the inflammatory responses accompanying tumour growth.
format Text
id pubmed-2009489
institution National Center for Biotechnology Information
language English
publishDate 1978
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20094892009-09-10 Immunoadherence and complement in cancer-bearing mice. Porta, C. Villa, M. L. Clerici, E. Br J Cancer Research Article Shortly after grafting of Ehrlich ascites carcinoma cells, the serum of tumour-bearing mice loses the capacity to mediate immunoadherence phenomena, because of a sharp decrease in the concentration of C3b and C3d, while the cellular receptors for such factors are unaffected by tumour growth. It is suggested that complement is consumed through the alternative pathway which is activated during the inflammatory responses accompanying tumour growth. Nature Publishing Group 1978-01 /pmc/articles/PMC2009489/ /pubmed/619956 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Porta, C.
Villa, M. L.
Clerici, E.
Immunoadherence and complement in cancer-bearing mice.
title Immunoadherence and complement in cancer-bearing mice.
title_full Immunoadherence and complement in cancer-bearing mice.
title_fullStr Immunoadherence and complement in cancer-bearing mice.
title_full_unstemmed Immunoadherence and complement in cancer-bearing mice.
title_short Immunoadherence and complement in cancer-bearing mice.
title_sort immunoadherence and complement in cancer-bearing mice.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009489/
https://www.ncbi.nlm.nih.gov/pubmed/619956
work_keys_str_mv AT portac immunoadherenceandcomplementincancerbearingmice
AT villaml immunoadherenceandcomplementincancerbearingmice
AT clericie immunoadherenceandcomplementincancerbearingmice

Ejemplares similares