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Arrest patterns of circulating lymphosarcoma cells in tumour-bearing mice as modified by previously injected cell suspensions.
The effects were determined of an initial i.v. injection of 0.2 ml suspensions of 125IUdR-labelled lymphosarcoma cells on the early arrest patterns of a second injection of cancer cells into tumour-bearing mice. The results indicate that interactions between the first injection and the host markedly...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1978
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009523/ https://www.ncbi.nlm.nih.gov/pubmed/580404 |
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author | Weiss, L. Glaves, D. |
author_facet | Weiss, L. Glaves, D. |
author_sort | Weiss, L. |
collection | PubMed |
description | The effects were determined of an initial i.v. injection of 0.2 ml suspensions of 125IUdR-labelled lymphosarcoma cells on the early arrest patterns of a second injection of cancer cells into tumour-bearing mice. The results indicate that interactions between the first injection and the host markedly affected the arrest pattern of the second dose in the lungs, but not the livers, of tumour-bearing animals. These observations are explained on the basis of the injected fluid volumes, which are considerable in mice, in relation to their total blood volumes of approximately 2 ml. |
format | Text |
id | pubmed-2009523 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1978 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20095232009-09-10 Arrest patterns of circulating lymphosarcoma cells in tumour-bearing mice as modified by previously injected cell suspensions. Weiss, L. Glaves, D. Br J Cancer Research Article The effects were determined of an initial i.v. injection of 0.2 ml suspensions of 125IUdR-labelled lymphosarcoma cells on the early arrest patterns of a second injection of cancer cells into tumour-bearing mice. The results indicate that interactions between the first injection and the host markedly affected the arrest pattern of the second dose in the lungs, but not the livers, of tumour-bearing animals. These observations are explained on the basis of the injected fluid volumes, which are considerable in mice, in relation to their total blood volumes of approximately 2 ml. Nature Publishing Group 1978-03 /pmc/articles/PMC2009523/ /pubmed/580404 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Weiss, L. Glaves, D. Arrest patterns of circulating lymphosarcoma cells in tumour-bearing mice as modified by previously injected cell suspensions. |
title | Arrest patterns of circulating lymphosarcoma cells in tumour-bearing mice as modified by previously injected cell suspensions. |
title_full | Arrest patterns of circulating lymphosarcoma cells in tumour-bearing mice as modified by previously injected cell suspensions. |
title_fullStr | Arrest patterns of circulating lymphosarcoma cells in tumour-bearing mice as modified by previously injected cell suspensions. |
title_full_unstemmed | Arrest patterns of circulating lymphosarcoma cells in tumour-bearing mice as modified by previously injected cell suspensions. |
title_short | Arrest patterns of circulating lymphosarcoma cells in tumour-bearing mice as modified by previously injected cell suspensions. |
title_sort | arrest patterns of circulating lymphosarcoma cells in tumour-bearing mice as modified by previously injected cell suspensions. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009523/ https://www.ncbi.nlm.nih.gov/pubmed/580404 |
work_keys_str_mv | AT weissl arrestpatternsofcirculatinglymphosarcomacellsintumourbearingmiceasmodifiedbypreviouslyinjectedcellsuspensions AT glavesd arrestpatternsofcirculatinglymphosarcomacellsintumourbearingmiceasmodifiedbypreviouslyinjectedcellsuspensions |