Failure of suckling to transfer immunity to a syngeneic rat sarcoma.

Young born to and suckled by mothers rendered immune to a syngeneic sarcoma showed no acquired resistance to challenge with tumour. Whilst other workers had found that allograft immunity could be transferred by milk, we conclude (1) that lymphocytes present in the milk cannot transfer immunity to tu...

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Detalles Bibliográficos
Autores principales: Eccles, S. A., Alexander, P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1978
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009532/
https://www.ncbi.nlm.nih.gov/pubmed/565208
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author Eccles, S. A.
Alexander, P.
author_facet Eccles, S. A.
Alexander, P.
author_sort Eccles, S. A.
collection PubMed
description Young born to and suckled by mothers rendered immune to a syngeneic sarcoma showed no acquired resistance to challenge with tumour. Whilst other workers had found that allograft immunity could be transferred by milk, we conclude (1) that lymphocytes present in the milk cannot transfer immunity to tumour-specific antigens when absorbed by suckling, and (2) that transfer of maternal immunoglobulins either pre- or postnatally also does not protect against s.c. inoculated tumour.
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spelling pubmed-20095322009-09-10 Failure of suckling to transfer immunity to a syngeneic rat sarcoma. Eccles, S. A. Alexander, P. Br J Cancer Research Article Young born to and suckled by mothers rendered immune to a syngeneic sarcoma showed no acquired resistance to challenge with tumour. Whilst other workers had found that allograft immunity could be transferred by milk, we conclude (1) that lymphocytes present in the milk cannot transfer immunity to tumour-specific antigens when absorbed by suckling, and (2) that transfer of maternal immunoglobulins either pre- or postnatally also does not protect against s.c. inoculated tumour. Nature Publishing Group 1978-03 /pmc/articles/PMC2009532/ /pubmed/565208 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Eccles, S. A.
Alexander, P.
Failure of suckling to transfer immunity to a syngeneic rat sarcoma.
title Failure of suckling to transfer immunity to a syngeneic rat sarcoma.
title_full Failure of suckling to transfer immunity to a syngeneic rat sarcoma.
title_fullStr Failure of suckling to transfer immunity to a syngeneic rat sarcoma.
title_full_unstemmed Failure of suckling to transfer immunity to a syngeneic rat sarcoma.
title_short Failure of suckling to transfer immunity to a syngeneic rat sarcoma.
title_sort failure of suckling to transfer immunity to a syngeneic rat sarcoma.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009532/
https://www.ncbi.nlm.nih.gov/pubmed/565208
work_keys_str_mv AT ecclessa failureofsucklingtotransferimmunitytoasyngeneicratsarcoma
AT alexanderp failureofsucklingtotransferimmunitytoasyngeneicratsarcoma

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