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Quantitative relationship between volume of tumour cell units and their intravascular survival.
The derivation of the median volume (MV) and the geometric standard deviation (SDg) for a suspension of tumour cells quantifies the size and distribution of tumour cell aggregates in the suspension. Data collected in a group of 14 experiments shwoed a significant correlation of 0.80 (P less than 0.0...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1978
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009575/ https://www.ncbi.nlm.nih.gov/pubmed/629862 |
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author | Lione, A. Bosmann, H. B. |
author_facet | Lione, A. Bosmann, H. B. |
author_sort | Lione, A. |
collection | PubMed |
description | The derivation of the median volume (MV) and the geometric standard deviation (SDg) for a suspension of tumour cells quantifies the size and distribution of tumour cell aggregates in the suspension. Data collected in a group of 14 experiments shwoed a significant correlation of 0.80 (P less than 0.001) between the number of lung tumours formed by a suspension of B16 melanoma cells injected i.v. into C57BL/6J mice and the product of the MV and SDg of each cell suspension. These data define a size parameter of tumour cell suspensions that correlates with the intravascular survival properties of tumour cells. |
format | Text |
id | pubmed-2009575 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1978 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20095752009-09-10 Quantitative relationship between volume of tumour cell units and their intravascular survival. Lione, A. Bosmann, H. B. Br J Cancer Research Article The derivation of the median volume (MV) and the geometric standard deviation (SDg) for a suspension of tumour cells quantifies the size and distribution of tumour cell aggregates in the suspension. Data collected in a group of 14 experiments shwoed a significant correlation of 0.80 (P less than 0.001) between the number of lung tumours formed by a suspension of B16 melanoma cells injected i.v. into C57BL/6J mice and the product of the MV and SDg of each cell suspension. These data define a size parameter of tumour cell suspensions that correlates with the intravascular survival properties of tumour cells. Nature Publishing Group 1978-02 /pmc/articles/PMC2009575/ /pubmed/629862 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Lione, A. Bosmann, H. B. Quantitative relationship between volume of tumour cell units and their intravascular survival. |
title | Quantitative relationship between volume of tumour cell units and their intravascular survival. |
title_full | Quantitative relationship between volume of tumour cell units and their intravascular survival. |
title_fullStr | Quantitative relationship between volume of tumour cell units and their intravascular survival. |
title_full_unstemmed | Quantitative relationship between volume of tumour cell units and their intravascular survival. |
title_short | Quantitative relationship between volume of tumour cell units and their intravascular survival. |
title_sort | quantitative relationship between volume of tumour cell units and their intravascular survival. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009575/ https://www.ncbi.nlm.nih.gov/pubmed/629862 |
work_keys_str_mv | AT lionea quantitativerelationshipbetweenvolumeoftumourcellunitsandtheirintravascularsurvival AT bosmannhb quantitativerelationshipbetweenvolumeoftumourcellunitsandtheirintravascularsurvival |