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Squamous Lesions in the Lungs of Rats Exposed to Tobacco-smoke-condensate Fractions by Repeated Intratracheal Instillation

Twice-weekly intratracheal instillations in rats of up to 24 mg of Fraction (R + P)G suspended in either infusine (I) or buffered saline/gelatine (BS/G) gave rise to foci of squamous metaplasia of alveolar epithelium (SqM) and squamous neoplasms (SqN). Fraction (R + P)G, which is a fraction of cigar...

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Detalles Bibliográficos
Autores principales: Simons, P. J., Lee, P. N., Roe, F. J. C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1978
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009662/
https://www.ncbi.nlm.nih.gov/pubmed/678436