Measurement of oestradiol receptors by five institutions on common tissue samples.

The soluble oestrogen-receptor content of common breast tumours has been measured by 5 different laboratories, each using their own assay procedure. Good agreement was achieved on whether a sample was positive or negative for oestrogen receptor. Qualitative differences between laboratories could be...

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Autores principales: King, R. J., Barnes, D. M., Hawkins, R. A., Leake, R. E., Maynard, P. V., Roberts, M. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1978
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009740/
https://www.ncbi.nlm.nih.gov/pubmed/708574
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author King, R. J.
Barnes, D. M.
Hawkins, R. A.
Leake, R. E.
Maynard, P. V.
Roberts, M. M.
author_facet King, R. J.
Barnes, D. M.
Hawkins, R. A.
Leake, R. E.
Maynard, P. V.
Roberts, M. M.
author_sort King, R. J.
collection PubMed
description The soluble oestrogen-receptor content of common breast tumours has been measured by 5 different laboratories, each using their own assay procedure. Good agreement was achieved on whether a sample was positive or negative for oestrogen receptor. Qualitative differences between laboratories could be explained by differences in thiol-reagent content of assay medium and by the method of homogenization. Recommendations are made on some of the factors involved in the routine assay of receptors in breast tumours.
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spelling pubmed-20097402009-09-10 Measurement of oestradiol receptors by five institutions on common tissue samples. King, R. J. Barnes, D. M. Hawkins, R. A. Leake, R. E. Maynard, P. V. Roberts, M. M. Br J Cancer Research Article The soluble oestrogen-receptor content of common breast tumours has been measured by 5 different laboratories, each using their own assay procedure. Good agreement was achieved on whether a sample was positive or negative for oestrogen receptor. Qualitative differences between laboratories could be explained by differences in thiol-reagent content of assay medium and by the method of homogenization. Recommendations are made on some of the factors involved in the routine assay of receptors in breast tumours. Nature Publishing Group 1978-09 /pmc/articles/PMC2009740/ /pubmed/708574 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
King, R. J.
Barnes, D. M.
Hawkins, R. A.
Leake, R. E.
Maynard, P. V.
Roberts, M. M.
Measurement of oestradiol receptors by five institutions on common tissue samples.
title Measurement of oestradiol receptors by five institutions on common tissue samples.
title_full Measurement of oestradiol receptors by five institutions on common tissue samples.
title_fullStr Measurement of oestradiol receptors by five institutions on common tissue samples.
title_full_unstemmed Measurement of oestradiol receptors by five institutions on common tissue samples.
title_short Measurement of oestradiol receptors by five institutions on common tissue samples.
title_sort measurement of oestradiol receptors by five institutions on common tissue samples.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009740/
https://www.ncbi.nlm.nih.gov/pubmed/708574
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