Relationship between oestrogen-receptor content and histological grade in human primary breast tumours.

A series of 300 patients presenting consecutively with primary operable breast cancer has been studied. A significant correlation was found between oestrogen-receptor (ER) content and histological grade: the better-differentiated tumours rarely lacked receptor. This correlation was significant only...

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Detalles Bibliográficos
Autores principales: Maynard, P. V., Davies, C. J., Blamey, R. W., Elston, C. W., Johnson, J., Griffiths, K.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1978
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009828/
https://www.ncbi.nlm.nih.gov/pubmed/743491
Descripción
Sumario:A series of 300 patients presenting consecutively with primary operable breast cancer has been studied. A significant correlation was found between oestrogen-receptor (ER) content and histological grade: the better-differentiated tumours rarely lacked receptor. This correlation was significant only in women defined as post-menopausal. Data on early recurrence of disease indicate a worse prognosis for women in whom primary tumours are ER-.

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