Relationship between oestrogen-receptor content and histological grade in human primary breast tumours.

A series of 300 patients presenting consecutively with primary operable breast cancer has been studied. A significant correlation was found between oestrogen-receptor (ER) content and histological grade: the better-differentiated tumours rarely lacked receptor. This correlation was significant only...

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Autores principales: Maynard, P. V., Davies, C. J., Blamey, R. W., Elston, C. W., Johnson, J., Griffiths, K.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1978
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009828/
https://www.ncbi.nlm.nih.gov/pubmed/743491
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author Maynard, P. V.
Davies, C. J.
Blamey, R. W.
Elston, C. W.
Johnson, J.
Griffiths, K.
author_facet Maynard, P. V.
Davies, C. J.
Blamey, R. W.
Elston, C. W.
Johnson, J.
Griffiths, K.
author_sort Maynard, P. V.
collection PubMed
description A series of 300 patients presenting consecutively with primary operable breast cancer has been studied. A significant correlation was found between oestrogen-receptor (ER) content and histological grade: the better-differentiated tumours rarely lacked receptor. This correlation was significant only in women defined as post-menopausal. Data on early recurrence of disease indicate a worse prognosis for women in whom primary tumours are ER-.
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spelling pubmed-20098282009-09-10 Relationship between oestrogen-receptor content and histological grade in human primary breast tumours. Maynard, P. V. Davies, C. J. Blamey, R. W. Elston, C. W. Johnson, J. Griffiths, K. Br J Cancer Research Article A series of 300 patients presenting consecutively with primary operable breast cancer has been studied. A significant correlation was found between oestrogen-receptor (ER) content and histological grade: the better-differentiated tumours rarely lacked receptor. This correlation was significant only in women defined as post-menopausal. Data on early recurrence of disease indicate a worse prognosis for women in whom primary tumours are ER-. Nature Publishing Group 1978-12 /pmc/articles/PMC2009828/ /pubmed/743491 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Maynard, P. V.
Davies, C. J.
Blamey, R. W.
Elston, C. W.
Johnson, J.
Griffiths, K.
Relationship between oestrogen-receptor content and histological grade in human primary breast tumours.
title Relationship between oestrogen-receptor content and histological grade in human primary breast tumours.
title_full Relationship between oestrogen-receptor content and histological grade in human primary breast tumours.
title_fullStr Relationship between oestrogen-receptor content and histological grade in human primary breast tumours.
title_full_unstemmed Relationship between oestrogen-receptor content and histological grade in human primary breast tumours.
title_short Relationship between oestrogen-receptor content and histological grade in human primary breast tumours.
title_sort relationship between oestrogen-receptor content and histological grade in human primary breast tumours.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009828/
https://www.ncbi.nlm.nih.gov/pubmed/743491
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