Serological aspects of rat tumour xenograft growth in athymic nude mice.

The serum of athymic nude mice bearing rat tumour xenografts has been examined for tumour-specific antigen. With a sarcoma and a hepatoma, tumour-specific antigen expression continued in xenograft growths, and sera of tumour-bearing mice contained free antigen, assayed by its ability to neutralise r...

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Detalles Bibliográficos
Autores principales: Pimm, M. V., Baldwin, R. W.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1979
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009841/
https://www.ncbi.nlm.nih.gov/pubmed/373782
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author Pimm, M. V.
Baldwin, R. W.
author_facet Pimm, M. V.
Baldwin, R. W.
author_sort Pimm, M. V.
collection PubMed
description The serum of athymic nude mice bearing rat tumour xenografts has been examined for tumour-specific antigen. With a sarcoma and a hepatoma, tumour-specific antigen expression continued in xenograft growths, and sera of tumour-bearing mice contained free antigen, assayed by its ability to neutralise reactivity of tumour-immune rat sera against tumour target cells in an indirect membrane-immunofluorescence test. In contrast, no anti-rat antibody was detectable in sera of mice bearing the xenografts, or rejecting cells injected in admixture with BCG.
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spelling pubmed-20098412009-09-10 Serological aspects of rat tumour xenograft growth in athymic nude mice. Pimm, M. V. Baldwin, R. W. Br J Cancer Research Article The serum of athymic nude mice bearing rat tumour xenografts has been examined for tumour-specific antigen. With a sarcoma and a hepatoma, tumour-specific antigen expression continued in xenograft growths, and sera of tumour-bearing mice contained free antigen, assayed by its ability to neutralise reactivity of tumour-immune rat sera against tumour target cells in an indirect membrane-immunofluorescence test. In contrast, no anti-rat antibody was detectable in sera of mice bearing the xenografts, or rejecting cells injected in admixture with BCG. Nature Publishing Group 1979-02 /pmc/articles/PMC2009841/ /pubmed/373782 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Pimm, M. V.
Baldwin, R. W.
Serological aspects of rat tumour xenograft growth in athymic nude mice.
title Serological aspects of rat tumour xenograft growth in athymic nude mice.
title_full Serological aspects of rat tumour xenograft growth in athymic nude mice.
title_fullStr Serological aspects of rat tumour xenograft growth in athymic nude mice.
title_full_unstemmed Serological aspects of rat tumour xenograft growth in athymic nude mice.
title_short Serological aspects of rat tumour xenograft growth in athymic nude mice.
title_sort serological aspects of rat tumour xenograft growth in athymic nude mice.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009841/
https://www.ncbi.nlm.nih.gov/pubmed/373782
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AT baldwinrw serologicalaspectsofrattumourxenograftgrowthinathymicnudemice

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