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Evidence for serum binding of oxidized spermine and its potent G1-phase inhibition of cell proliferation.
Serum polyamine oxidase (EC 1.4.3.4) is known to react in vitro with radio-labelled spermine4+ to produce di-oxidized spermine which must incorporate the label. Di-oxidized spermine was compatible with a radio-labelled compound2+ separated from the reaction mixture by ion-exchange chromatography. Th...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1979
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009892/ https://www.ncbi.nlm.nih.gov/pubmed/486311 |