A human testicular teratoma serially transplanted in immune-deprived mice.

Serial transplantation of an HCG-producing human testicular teratoma in immune-deprived mice is described. The xenografted tumour was compared to the tumour of origin in histology, immunohistochemistry (using an immune peroxidase technique to localize HCG) autoradiography, marker production and grow...

Descripción completa

Detalles Bibliográficos
Autores principales: Selby, P. J., Heyderman, E., Gibbs, J., Peckham, M. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1979
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009907/
https://www.ncbi.nlm.nih.gov/pubmed/385030
_version_ 1782136210624348160
author Selby, P. J.
Heyderman, E.
Gibbs, J.
Peckham, M. J.
author_facet Selby, P. J.
Heyderman, E.
Gibbs, J.
Peckham, M. J.
author_sort Selby, P. J.
collection PubMed
description Serial transplantation of an HCG-producing human testicular teratoma in immune-deprived mice is described. The xenografted tumour was compared to the tumour of origin in histology, immunohistochemistry (using an immune peroxidase technique to localize HCG) autoradiography, marker production and growth rate. It is concluded that the xenograft retained the characteristics of the original tumour with the exception of a reduction in HCG-producing elements at transplantation beyond 5 serial passages. IMAGES:
format Text
id pubmed-2009907
institution National Center for Biotechnology Information
language English
publishDate 1979
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20099072009-09-10 A human testicular teratoma serially transplanted in immune-deprived mice. Selby, P. J. Heyderman, E. Gibbs, J. Peckham, M. J. Br J Cancer Research Article Serial transplantation of an HCG-producing human testicular teratoma in immune-deprived mice is described. The xenografted tumour was compared to the tumour of origin in histology, immunohistochemistry (using an immune peroxidase technique to localize HCG) autoradiography, marker production and growth rate. It is concluded that the xenograft retained the characteristics of the original tumour with the exception of a reduction in HCG-producing elements at transplantation beyond 5 serial passages. IMAGES: Nature Publishing Group 1979-05 /pmc/articles/PMC2009907/ /pubmed/385030 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Selby, P. J.
Heyderman, E.
Gibbs, J.
Peckham, M. J.
A human testicular teratoma serially transplanted in immune-deprived mice.
title A human testicular teratoma serially transplanted in immune-deprived mice.
title_full A human testicular teratoma serially transplanted in immune-deprived mice.
title_fullStr A human testicular teratoma serially transplanted in immune-deprived mice.
title_full_unstemmed A human testicular teratoma serially transplanted in immune-deprived mice.
title_short A human testicular teratoma serially transplanted in immune-deprived mice.
title_sort human testicular teratoma serially transplanted in immune-deprived mice.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009907/
https://www.ncbi.nlm.nih.gov/pubmed/385030
work_keys_str_mv AT selbypj ahumantesticularteratomaseriallytransplantedinimmunedeprivedmice
AT heydermane ahumantesticularteratomaseriallytransplantedinimmunedeprivedmice
AT gibbsj ahumantesticularteratomaseriallytransplantedinimmunedeprivedmice
AT peckhammj ahumantesticularteratomaseriallytransplantedinimmunedeprivedmice
AT selbypj humantesticularteratomaseriallytransplantedinimmunedeprivedmice
AT heydermane humantesticularteratomaseriallytransplantedinimmunedeprivedmice
AT gibbsj humantesticularteratomaseriallytransplantedinimmunedeprivedmice
AT peckhammj humantesticularteratomaseriallytransplantedinimmunedeprivedmice

Ejemplares similares