Lack of effect of immunotherapy with BCG and Corynebacterium parvum on hepatic drug hydroxylation in man.

Serial serum diphenylhydantoin and urinary 5-(p-hydroxphenyl)-5-phenylhydantoin concentrations were determined in 8 patients with malignant disease and 4 healthy volunteers on 2 separate occasions after an oral dose of diphenylhydantoin (500 mg). No significant difference was observed between metabo...

Descripción completa

Detalles Bibliográficos
Autores principales: Wan, H. H., Thatcher, N., Mullen, P. W., Smith, G. N., Wilkinson, P. M.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1979
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009933/
https://www.ncbi.nlm.nih.gov/pubmed/444399
_version_ 1782136215485546496
author Wan, H. H.
Thatcher, N.
Mullen, P. W.
Smith, G. N.
Wilkinson, P. M.
author_facet Wan, H. H.
Thatcher, N.
Mullen, P. W.
Smith, G. N.
Wilkinson, P. M.
author_sort Wan, H. H.
collection PubMed
description Serial serum diphenylhydantoin and urinary 5-(p-hydroxphenyl)-5-phenylhydantoin concentrations were determined in 8 patients with malignant disease and 4 healthy volunteers on 2 separate occasions after an oral dose of diphenylhydantoin (500 mg). No significant difference was observed between metabolism before and 10 days after immunization with BCG or Corynebacterium parvum. Volunteers without intervening immunization similarly showed no difference.
format Text
id pubmed-2009933
institution National Center for Biotechnology Information
language English
publishDate 1979
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20099332009-09-10 Lack of effect of immunotherapy with BCG and Corynebacterium parvum on hepatic drug hydroxylation in man. Wan, H. H. Thatcher, N. Mullen, P. W. Smith, G. N. Wilkinson, P. M. Br J Cancer Research Article Serial serum diphenylhydantoin and urinary 5-(p-hydroxphenyl)-5-phenylhydantoin concentrations were determined in 8 patients with malignant disease and 4 healthy volunteers on 2 separate occasions after an oral dose of diphenylhydantoin (500 mg). No significant difference was observed between metabolism before and 10 days after immunization with BCG or Corynebacterium parvum. Volunteers without intervening immunization similarly showed no difference. Nature Publishing Group 1979-04 /pmc/articles/PMC2009933/ /pubmed/444399 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Wan, H. H.
Thatcher, N.
Mullen, P. W.
Smith, G. N.
Wilkinson, P. M.
Lack of effect of immunotherapy with BCG and Corynebacterium parvum on hepatic drug hydroxylation in man.
title Lack of effect of immunotherapy with BCG and Corynebacterium parvum on hepatic drug hydroxylation in man.
title_full Lack of effect of immunotherapy with BCG and Corynebacterium parvum on hepatic drug hydroxylation in man.
title_fullStr Lack of effect of immunotherapy with BCG and Corynebacterium parvum on hepatic drug hydroxylation in man.
title_full_unstemmed Lack of effect of immunotherapy with BCG and Corynebacterium parvum on hepatic drug hydroxylation in man.
title_short Lack of effect of immunotherapy with BCG and Corynebacterium parvum on hepatic drug hydroxylation in man.
title_sort lack of effect of immunotherapy with bcg and corynebacterium parvum on hepatic drug hydroxylation in man.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009933/
https://www.ncbi.nlm.nih.gov/pubmed/444399
work_keys_str_mv AT wanhh lackofeffectofimmunotherapywithbcgandcorynebacteriumparvumonhepaticdrughydroxylationinman
AT thatchern lackofeffectofimmunotherapywithbcgandcorynebacteriumparvumonhepaticdrughydroxylationinman
AT mullenpw lackofeffectofimmunotherapywithbcgandcorynebacteriumparvumonhepaticdrughydroxylationinman
AT smithgn lackofeffectofimmunotherapywithbcgandcorynebacteriumparvumonhepaticdrughydroxylationinman
AT wilkinsonpm lackofeffectofimmunotherapywithbcgandcorynebacteriumparvumonhepaticdrughydroxylationinman

Ejemplares similares