Histological grade and other prognostic factors in relation to survival of patients with breast cancer.

Records of 3085 patients registered with breast cancer at the Mersey Regional Cancer Registry have been analysed to evaluate the relative importance of possible prognostic factors. In a subgroup of 1759 patients, clinical stage and histological grade are shown to be strongly related to survival afte...

Descripción completa

Detalles Bibliográficos
Autores principales: Freedman, L. S., Edwards, D. N., McConnell, E. M., Downham, D. Y.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1979
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009958/
https://www.ncbi.nlm.nih.gov/pubmed/454563
_version_ 1782136220813361152
author Freedman, L. S.
Edwards, D. N.
McConnell, E. M.
Downham, D. Y.
author_facet Freedman, L. S.
Edwards, D. N.
McConnell, E. M.
Downham, D. Y.
author_sort Freedman, L. S.
collection PubMed
description Records of 3085 patients registered with breast cancer at the Mersey Regional Cancer Registry have been analysed to evaluate the relative importance of possible prognostic factors. In a subgroup of 1759 patients, clinical stage and histological grade are shown to be strongly related to survival after treatment. In addition histological grade is related to the distribution of times to death after treatment. The results of this and 3 other studies have implications for the design and analysis of clinical trials in the primary treatment of breast cancer. IMAGES:
format Text
id pubmed-2009958
institution National Center for Biotechnology Information
language English
publishDate 1979
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20099582009-09-10 Histological grade and other prognostic factors in relation to survival of patients with breast cancer. Freedman, L. S. Edwards, D. N. McConnell, E. M. Downham, D. Y. Br J Cancer Research Article Records of 3085 patients registered with breast cancer at the Mersey Regional Cancer Registry have been analysed to evaluate the relative importance of possible prognostic factors. In a subgroup of 1759 patients, clinical stage and histological grade are shown to be strongly related to survival after treatment. In addition histological grade is related to the distribution of times to death after treatment. The results of this and 3 other studies have implications for the design and analysis of clinical trials in the primary treatment of breast cancer. IMAGES: Nature Publishing Group 1979-07 /pmc/articles/PMC2009958/ /pubmed/454563 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Freedman, L. S.
Edwards, D. N.
McConnell, E. M.
Downham, D. Y.
Histological grade and other prognostic factors in relation to survival of patients with breast cancer.
title Histological grade and other prognostic factors in relation to survival of patients with breast cancer.
title_full Histological grade and other prognostic factors in relation to survival of patients with breast cancer.
title_fullStr Histological grade and other prognostic factors in relation to survival of patients with breast cancer.
title_full_unstemmed Histological grade and other prognostic factors in relation to survival of patients with breast cancer.
title_short Histological grade and other prognostic factors in relation to survival of patients with breast cancer.
title_sort histological grade and other prognostic factors in relation to survival of patients with breast cancer.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009958/
https://www.ncbi.nlm.nih.gov/pubmed/454563
work_keys_str_mv AT freedmanls histologicalgradeandotherprognosticfactorsinrelationtosurvivalofpatientswithbreastcancer
AT edwardsdn histologicalgradeandotherprognosticfactorsinrelationtosurvivalofpatientswithbreastcancer
AT mcconnellem histologicalgradeandotherprognosticfactorsinrelationtosurvivalofpatientswithbreastcancer
AT downhamdy histologicalgradeandotherprognosticfactorsinrelationtosurvivalofpatientswithbreastcancer

Ejemplares similares