Antibody-dependent and spontaneous lympholysis in urologic cancer patients.

To evaluate cytotoxic function mediated by killer lymphocytes and macrophages in urological cancer patients, we examined antibody-dependent and spontaneous lympholysis of chicken erythrocyte target cells, which is mediated by macrophages. Our results demonstrate a discordance between cytotoxic mecha...

Descripción completa

Detalles Bibliográficos
Autores principales: Ratliff, T. L., McCool, R. E., Catalona, W. J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1979
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009983/
https://www.ncbi.nlm.nih.gov/pubmed/444405
_version_ 1782136225991229440
author Ratliff, T. L.
McCool, R. E.
Catalona, W. J.
author_facet Ratliff, T. L.
McCool, R. E.
Catalona, W. J.
author_sort Ratliff, T. L.
collection PubMed
description To evaluate cytotoxic function mediated by killer lymphocytes and macrophages in urological cancer patients, we examined antibody-dependent and spontaneous lympholysis of chicken erythrocyte target cells, which is mediated by macrophages. Our results demonstrate a discordance between cytotoxic mechanisms in cancer patients, killer-cell function being impaired whilst macrophage-mediated cytotoxicity was increased.
format Text
id pubmed-2009983
institution National Center for Biotechnology Information
language English
publishDate 1979
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20099832009-09-10 Antibody-dependent and spontaneous lympholysis in urologic cancer patients. Ratliff, T. L. McCool, R. E. Catalona, W. J. Br J Cancer Research Article To evaluate cytotoxic function mediated by killer lymphocytes and macrophages in urological cancer patients, we examined antibody-dependent and spontaneous lympholysis of chicken erythrocyte target cells, which is mediated by macrophages. Our results demonstrate a discordance between cytotoxic mechanisms in cancer patients, killer-cell function being impaired whilst macrophage-mediated cytotoxicity was increased. Nature Publishing Group 1979-06 /pmc/articles/PMC2009983/ /pubmed/444405 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Ratliff, T. L.
McCool, R. E.
Catalona, W. J.
Antibody-dependent and spontaneous lympholysis in urologic cancer patients.
title Antibody-dependent and spontaneous lympholysis in urologic cancer patients.
title_full Antibody-dependent and spontaneous lympholysis in urologic cancer patients.
title_fullStr Antibody-dependent and spontaneous lympholysis in urologic cancer patients.
title_full_unstemmed Antibody-dependent and spontaneous lympholysis in urologic cancer patients.
title_short Antibody-dependent and spontaneous lympholysis in urologic cancer patients.
title_sort antibody-dependent and spontaneous lympholysis in urologic cancer patients.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2009983/
https://www.ncbi.nlm.nih.gov/pubmed/444405
work_keys_str_mv AT ratlifftl antibodydependentandspontaneouslympholysisinurologiccancerpatients
AT mccoolre antibodydependentandspontaneouslympholysisinurologiccancerpatients
AT catalonawj antibodydependentandspontaneouslympholysisinurologiccancerpatients

Ejemplares similares