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Racial differences in melanoma incidence.
The incidences of malignant melanoma recorded by 59 population-based cancer registries were investigated to determine the effects of racial and skin-colour differences. White populations exhibited a wide range of melanoma incidences and females commonly, though not invariably, had a higher incidence...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1979
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010011/ https://www.ncbi.nlm.nih.gov/pubmed/475965 |
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author | Crombie, I. K. |
author_facet | Crombie, I. K. |
author_sort | Crombie, I. K. |
collection | PubMed |
description | The incidences of malignant melanoma recorded by 59 population-based cancer registries were investigated to determine the effects of racial and skin-colour differences. White populations exhibited a wide range of melanoma incidences and females commonly, though not invariably, had a higher incidence than males. Non-white populations experienced in general a much lower incidence of melanoma although there was some overlap of white and non-white rates. No predominant sex difference emerged among non-whites. Populations of African descent were found to have a higher incidence than those of Asiatic origin, but it was concluded that this was due largely to the high frequency of tumours among Africans on the sole of the foot. A clear negative correlation between degree of skin pigmentation and melanoma incidence emerged for the exposed body sites. These data provide strong support for the hypotheses that UV radiation is a major cause of malignant melanoma and that melanin pigmentation protects against it. Further research is required to elucidate the aetiology of melanoma of the sole of the foot. |
format | Text |
id | pubmed-2010011 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1979 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20100112009-09-10 Racial differences in melanoma incidence. Crombie, I. K. Br J Cancer Research Article The incidences of malignant melanoma recorded by 59 population-based cancer registries were investigated to determine the effects of racial and skin-colour differences. White populations exhibited a wide range of melanoma incidences and females commonly, though not invariably, had a higher incidence than males. Non-white populations experienced in general a much lower incidence of melanoma although there was some overlap of white and non-white rates. No predominant sex difference emerged among non-whites. Populations of African descent were found to have a higher incidence than those of Asiatic origin, but it was concluded that this was due largely to the high frequency of tumours among Africans on the sole of the foot. A clear negative correlation between degree of skin pigmentation and melanoma incidence emerged for the exposed body sites. These data provide strong support for the hypotheses that UV radiation is a major cause of malignant melanoma and that melanin pigmentation protects against it. Further research is required to elucidate the aetiology of melanoma of the sole of the foot. Nature Publishing Group 1979-08 /pmc/articles/PMC2010011/ /pubmed/475965 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Crombie, I. K. Racial differences in melanoma incidence. |
title | Racial differences in melanoma incidence. |
title_full | Racial differences in melanoma incidence. |
title_fullStr | Racial differences in melanoma incidence. |
title_full_unstemmed | Racial differences in melanoma incidence. |
title_short | Racial differences in melanoma incidence. |
title_sort | racial differences in melanoma incidence. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010011/ https://www.ncbi.nlm.nih.gov/pubmed/475965 |
work_keys_str_mv | AT crombieik racialdifferencesinmelanomaincidence |