Bovine ocular squamous-cell carcinoma: lymphocyte response to phytohaemagglutinin and tumour antigen.

The presence of ocular squamous-cell carcinomas in cattle was associated with significantly lower blastogenic response of peripheral-blood cultures to PHA than that of age-matched control cattle. The difference in blastogenic response was more marked when the external diameter of the tumour exceeded...

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Detalles Bibliográficos
Autores principales: Jennings, P. A., Lavin, M. F., Hughes, D. J., Spradbrow, P. B.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1979
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010090/
https://www.ncbi.nlm.nih.gov/pubmed/497111
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author Jennings, P. A.
Lavin, M. F.
Hughes, D. J.
Spradbrow, P. B.
author_facet Jennings, P. A.
Lavin, M. F.
Hughes, D. J.
Spradbrow, P. B.
author_sort Jennings, P. A.
collection PubMed
description The presence of ocular squamous-cell carcinomas in cattle was associated with significantly lower blastogenic response of peripheral-blood cultures to PHA than that of age-matched control cattle. The difference in blastogenic response was more marked when the external diameter of the tumour exceeded 2 cm. Cattle with aquamous-cell carcinomas had cell-mediated immunity against tumour extracts, as measured by the leucocyte adherence inhibition (LAI) microassay. The LAI reaction against tumour extracts was directly proportional to the general level of cell-mediated immunity as demonstrated by the lymphoproliferative response to PHA.
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spelling pubmed-20100902009-09-10 Bovine ocular squamous-cell carcinoma: lymphocyte response to phytohaemagglutinin and tumour antigen. Jennings, P. A. Lavin, M. F. Hughes, D. J. Spradbrow, P. B. Br J Cancer Research Article The presence of ocular squamous-cell carcinomas in cattle was associated with significantly lower blastogenic response of peripheral-blood cultures to PHA than that of age-matched control cattle. The difference in blastogenic response was more marked when the external diameter of the tumour exceeded 2 cm. Cattle with aquamous-cell carcinomas had cell-mediated immunity against tumour extracts, as measured by the leucocyte adherence inhibition (LAI) microassay. The LAI reaction against tumour extracts was directly proportional to the general level of cell-mediated immunity as demonstrated by the lymphoproliferative response to PHA. Nature Publishing Group 1979-10 /pmc/articles/PMC2010090/ /pubmed/497111 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Jennings, P. A.
Lavin, M. F.
Hughes, D. J.
Spradbrow, P. B.
Bovine ocular squamous-cell carcinoma: lymphocyte response to phytohaemagglutinin and tumour antigen.
title Bovine ocular squamous-cell carcinoma: lymphocyte response to phytohaemagglutinin and tumour antigen.
title_full Bovine ocular squamous-cell carcinoma: lymphocyte response to phytohaemagglutinin and tumour antigen.
title_fullStr Bovine ocular squamous-cell carcinoma: lymphocyte response to phytohaemagglutinin and tumour antigen.
title_full_unstemmed Bovine ocular squamous-cell carcinoma: lymphocyte response to phytohaemagglutinin and tumour antigen.
title_short Bovine ocular squamous-cell carcinoma: lymphocyte response to phytohaemagglutinin and tumour antigen.
title_sort bovine ocular squamous-cell carcinoma: lymphocyte response to phytohaemagglutinin and tumour antigen.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010090/
https://www.ncbi.nlm.nih.gov/pubmed/497111
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AT lavinmf bovineocularsquamouscellcarcinomalymphocyteresponsetophytohaemagglutininandtumourantigen
AT hughesdj bovineocularsquamouscellcarcinomalymphocyteresponsetophytohaemagglutininandtumourantigen
AT spradbrowpb bovineocularsquamouscellcarcinomalymphocyteresponsetophytohaemagglutininandtumourantigen

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