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Vitamin A, zinc and lung cancer.
Serum vitamin A concentration were measured in 26 newly diagnosed lung-cancer patients and found to be significantly lower than those of patients of similar age with either non-malignant lung or non-lung diseases. The levels of vitamin A in the lung-cancer patients, but not in the controls, were sig...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1979
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010126/ https://www.ncbi.nlm.nih.gov/pubmed/575048 |
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author | Atukorala, S. Basu, T. K. Dickerson, J. W. Donaldson, D. Sakula, A. |
author_facet | Atukorala, S. Basu, T. K. Dickerson, J. W. Donaldson, D. Sakula, A. |
author_sort | Atukorala, S. |
collection | PubMed |
description | Serum vitamin A concentration were measured in 26 newly diagnosed lung-cancer patients and found to be significantly lower than those of patients of similar age with either non-malignant lung or non-lung diseases. The levels of vitamin A in the lung-cancer patients, but not in the controls, were significantly correlated with serum concentrations of retinol-binding protein (RBP) and zinc. It is suggested that low levels of zinc might reduce the synthesis of RBP and thus reduce the mobilization of vitamin A from the liver. |
format | Text |
id | pubmed-2010126 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1979 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20101262009-09-10 Vitamin A, zinc and lung cancer. Atukorala, S. Basu, T. K. Dickerson, J. W. Donaldson, D. Sakula, A. Br J Cancer Research Article Serum vitamin A concentration were measured in 26 newly diagnosed lung-cancer patients and found to be significantly lower than those of patients of similar age with either non-malignant lung or non-lung diseases. The levels of vitamin A in the lung-cancer patients, but not in the controls, were significantly correlated with serum concentrations of retinol-binding protein (RBP) and zinc. It is suggested that low levels of zinc might reduce the synthesis of RBP and thus reduce the mobilization of vitamin A from the liver. Nature Publishing Group 1979-12 /pmc/articles/PMC2010126/ /pubmed/575048 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Atukorala, S. Basu, T. K. Dickerson, J. W. Donaldson, D. Sakula, A. Vitamin A, zinc and lung cancer. |
title | Vitamin A, zinc and lung cancer. |
title_full | Vitamin A, zinc and lung cancer. |
title_fullStr | Vitamin A, zinc and lung cancer. |
title_full_unstemmed | Vitamin A, zinc and lung cancer. |
title_short | Vitamin A, zinc and lung cancer. |
title_sort | vitamin a, zinc and lung cancer. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010126/ https://www.ncbi.nlm.nih.gov/pubmed/575048 |
work_keys_str_mv | AT atukoralas vitaminazincandlungcancer AT basutk vitaminazincandlungcancer AT dickersonjw vitaminazincandlungcancer AT donaldsond vitaminazincandlungcancer AT sakulaa vitaminazincandlungcancer |