ESR investigation of paraffin-embedded ocular melanomas.

Ocular melanomas embedded in paraffin wax for histological examination have been studied by electron spin resonance (ESR) spectroscopy. A free-radical signal was detected at the g = 2.003 section of the spectrum. The amplitude of this signal was correlated with the number of melanin granules in micr...

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Detalles Bibliográficos
Autores principales: Elek, G., Lapis, K., Rockenbauer, A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1980
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010198/
https://www.ncbi.nlm.nih.gov/pubmed/6245671
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author Elek, G.
Lapis, K.
Rockenbauer, A.
author_facet Elek, G.
Lapis, K.
Rockenbauer, A.
author_sort Elek, G.
collection PubMed
description Ocular melanomas embedded in paraffin wax for histological examination have been studied by electron spin resonance (ESR) spectroscopy. A free-radical signal was detected at the g = 2.003 section of the spectrum. The amplitude of this signal was correlated with the number of melanin granules in microscopical slides made from the tumour. This positive correlation can make ESR spectroscopy suitable for estimating the melanin content in the embedded melanoma blocks. Additional paramagnetic signals can also be detected. The clarification of their significance needs, however, further ESR measurements.
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spelling pubmed-20101982009-09-10 ESR investigation of paraffin-embedded ocular melanomas. Elek, G. Lapis, K. Rockenbauer, A. Br J Cancer Research Article Ocular melanomas embedded in paraffin wax for histological examination have been studied by electron spin resonance (ESR) spectroscopy. A free-radical signal was detected at the g = 2.003 section of the spectrum. The amplitude of this signal was correlated with the number of melanin granules in microscopical slides made from the tumour. This positive correlation can make ESR spectroscopy suitable for estimating the melanin content in the embedded melanoma blocks. Additional paramagnetic signals can also be detected. The clarification of their significance needs, however, further ESR measurements. Nature Publishing Group 1980-02 /pmc/articles/PMC2010198/ /pubmed/6245671 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Elek, G.
Lapis, K.
Rockenbauer, A.
ESR investigation of paraffin-embedded ocular melanomas.
title ESR investigation of paraffin-embedded ocular melanomas.
title_full ESR investigation of paraffin-embedded ocular melanomas.
title_fullStr ESR investigation of paraffin-embedded ocular melanomas.
title_full_unstemmed ESR investigation of paraffin-embedded ocular melanomas.
title_short ESR investigation of paraffin-embedded ocular melanomas.
title_sort esr investigation of paraffin-embedded ocular melanomas.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010198/
https://www.ncbi.nlm.nih.gov/pubmed/6245671
work_keys_str_mv AT elekg esrinvestigationofparaffinembeddedocularmelanomas
AT lapisk esrinvestigationofparaffinembeddedocularmelanomas
AT rockenbauera esrinvestigationofparaffinembeddedocularmelanomas

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