Suppressive factor of tumour origin against macrophage phagocytosis of Staphylococcus aureus.

Peritoneal macrophages from Sarcoma-180-bearing mice against Staphylococcus aureus were studied to determine the in vitro phagocytic capacities. When the phagocytic system was opsonized with normal mouse serum, macrophage phagocytic activity increased markedly soon after tumour graft and then return...

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Autores principales: Saito, H., Tomioka, H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1980
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010204/
https://www.ncbi.nlm.nih.gov/pubmed/7189404
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author Saito, H.
Tomioka, H.
author_facet Saito, H.
Tomioka, H.
author_sort Saito, H.
collection PubMed
description Peritoneal macrophages from Sarcoma-180-bearing mice against Staphylococcus aureus were studied to determine the in vitro phagocytic capacities. When the phagocytic system was opsonized with normal mouse serum, macrophage phagocytic activity increased markedly soon after tumour graft and then returned to normal. A new antiphagocytic factor was detected in the serum of tumour-bearers soon after tumour implantation. This factor was of tumour origin, stable even at a temperature of 56 degrees C for 30 min and non-dialysable. Peptone-starch-induced macrophages were less sensitive to the factor than their unstimulated counterpart.
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spelling pubmed-20102042009-09-10 Suppressive factor of tumour origin against macrophage phagocytosis of Staphylococcus aureus. Saito, H. Tomioka, H. Br J Cancer Research Article Peritoneal macrophages from Sarcoma-180-bearing mice against Staphylococcus aureus were studied to determine the in vitro phagocytic capacities. When the phagocytic system was opsonized with normal mouse serum, macrophage phagocytic activity increased markedly soon after tumour graft and then returned to normal. A new antiphagocytic factor was detected in the serum of tumour-bearers soon after tumour implantation. This factor was of tumour origin, stable even at a temperature of 56 degrees C for 30 min and non-dialysable. Peptone-starch-induced macrophages were less sensitive to the factor than their unstimulated counterpart. Nature Publishing Group 1980-02 /pmc/articles/PMC2010204/ /pubmed/7189404 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Saito, H.
Tomioka, H.
Suppressive factor of tumour origin against macrophage phagocytosis of Staphylococcus aureus.
title Suppressive factor of tumour origin against macrophage phagocytosis of Staphylococcus aureus.
title_full Suppressive factor of tumour origin against macrophage phagocytosis of Staphylococcus aureus.
title_fullStr Suppressive factor of tumour origin against macrophage phagocytosis of Staphylococcus aureus.
title_full_unstemmed Suppressive factor of tumour origin against macrophage phagocytosis of Staphylococcus aureus.
title_short Suppressive factor of tumour origin against macrophage phagocytosis of Staphylococcus aureus.
title_sort suppressive factor of tumour origin against macrophage phagocytosis of staphylococcus aureus.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010204/
https://www.ncbi.nlm.nih.gov/pubmed/7189404
work_keys_str_mv AT saitoh suppressivefactoroftumouroriginagainstmacrophagephagocytosisofstaphylococcusaureus
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