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Effects of local hyperthermia on the pharmacokinetics of misonidazole in the anaesthetized mouse.

The effects of sodium pentobarbitone anaesthesia, the presence of a tumour, and local hyperthermia to a tumour-bearing leg, on the pharmacokinetics of MISO in the mouse are reported. Analysis of MISO and its metabolite Ro 05-9963 was by high-performance liquid chromatography. The plasma kinetics of...

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Detalles Bibliográficos
Autores principales:	Honess, D. J., Workman, P., Morgan, J. E., Bleehen, N. M.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1980
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010260/ https://www.ncbi.nlm.nih.gov/pubmed/7387851

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