The heat shock protein 90 of Plasmodium falciparum and antimalarial activity of its inhibitor, geldanamycin

BACKGROUND: The naturally occurring benzoquinone ansamycin compound, geldanamycin (GA), is a specific inhibitor of heat shock protein 90 (Hsp90) and is a potential anticancer agent. Since Plasmodium falciparum has been reported to have an Hsp90 ortholog, we tested the possibility that GA might inhib...

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Detalles Bibliográficos
Autores principales: Kumar, Rajinder, Musiyenko, Alla, Barik, Sailen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC201030/
https://www.ncbi.nlm.nih.gov/pubmed/14514358
http://dx.doi.org/10.1186/1475-2875-2-30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC201030/
https://www.ncbi.nlm.nih.gov/pubmed/14514358
http://dx.doi.org/10.1186/1475-2875-2-30

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