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The heat shock protein 90 of Plasmodium falciparum and antimalarial activity of its inhibitor, geldanamycin
BACKGROUND: The naturally occurring benzoquinone ansamycin compound, geldanamycin (GA), is a specific inhibitor of heat shock protein 90 (Hsp90) and is a potential anticancer agent. Since Plasmodium falciparum has been reported to have an Hsp90 ortholog, we tested the possibility that GA might inhib...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC201030/ https://www.ncbi.nlm.nih.gov/pubmed/14514358 http://dx.doi.org/10.1186/1475-2875-2-30 |