Increased monocyte-mediated antibody-dependent cellular cytotoxicity (ADCC) in Hodgkin's disease.

Monocyte-mediated antibody-dependent cellular cytotoxicity (ADCC) was tested in 23 patients with histologically proven Hodgkin's disease and 29 healthy normal controls. Seven patients presented with active and 16 with inactive disease. The lytic capacity of the individual monocytes was signific...

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Autores principales: Pehamberger, H., Ludwig, H., Pötzi, P., Knapp, W.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1980
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010310/
https://www.ncbi.nlm.nih.gov/pubmed/7426302
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author Pehamberger, H.
Ludwig, H.
Pötzi, P.
Knapp, W.
author_facet Pehamberger, H.
Ludwig, H.
Pötzi, P.
Knapp, W.
author_sort Pehamberger, H.
collection PubMed
description Monocyte-mediated antibody-dependent cellular cytotoxicity (ADCC) was tested in 23 patients with histologically proven Hodgkin's disease and 29 healthy normal controls. Seven patients presented with active and 16 with inactive disease. The lytic capacity of the individual monocytes was significantly (P < 0.02) higher in patients with Hodgkin's disease than in normals. However, no significant difference was found between the numbers of monocytes in both groups of individuals, as determined by non-specific esterase staining. No correlation was found between the lytic capacity of monocytes and the activity of the disease.
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spelling pubmed-20103102009-09-10 Increased monocyte-mediated antibody-dependent cellular cytotoxicity (ADCC) in Hodgkin's disease. Pehamberger, H. Ludwig, H. Pötzi, P. Knapp, W. Br J Cancer Research Article Monocyte-mediated antibody-dependent cellular cytotoxicity (ADCC) was tested in 23 patients with histologically proven Hodgkin's disease and 29 healthy normal controls. Seven patients presented with active and 16 with inactive disease. The lytic capacity of the individual monocytes was significantly (P < 0.02) higher in patients with Hodgkin's disease than in normals. However, no significant difference was found between the numbers of monocytes in both groups of individuals, as determined by non-specific esterase staining. No correlation was found between the lytic capacity of monocytes and the activity of the disease. Nature Publishing Group 1980-05 /pmc/articles/PMC2010310/ /pubmed/7426302 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Pehamberger, H.
Ludwig, H.
Pötzi, P.
Knapp, W.
Increased monocyte-mediated antibody-dependent cellular cytotoxicity (ADCC) in Hodgkin's disease.
title Increased monocyte-mediated antibody-dependent cellular cytotoxicity (ADCC) in Hodgkin's disease.
title_full Increased monocyte-mediated antibody-dependent cellular cytotoxicity (ADCC) in Hodgkin's disease.
title_fullStr Increased monocyte-mediated antibody-dependent cellular cytotoxicity (ADCC) in Hodgkin's disease.
title_full_unstemmed Increased monocyte-mediated antibody-dependent cellular cytotoxicity (ADCC) in Hodgkin's disease.
title_short Increased monocyte-mediated antibody-dependent cellular cytotoxicity (ADCC) in Hodgkin's disease.
title_sort increased monocyte-mediated antibody-dependent cellular cytotoxicity (adcc) in hodgkin's disease.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010310/
https://www.ncbi.nlm.nih.gov/pubmed/7426302
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AT potzip increasedmonocytemediatedantibodydependentcellularcytotoxicityadccinhodgkinsdisease
AT knappw increasedmonocytemediatedantibodydependentcellularcytotoxicityadccinhodgkinsdisease

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