Prognostic implications of mean nuclear diameter in breast cancer.

The mean nuclear diameter of 100 breast cancers was measured on tissue sections, to evaluate its importance for early prognosis. The cases were subdivided into 3 subgroups: small (25.5% of cases), medium (63.3%) and large (11.2%) nuclei. Early recurrence and mortality rates were investigated in each...

Descripción completa

Detalles Bibliográficos
Autores principales: van Bogaert, L. J., de Muylder, C., Maldague, P., Maisin, H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1980
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010448/
https://www.ncbi.nlm.nih.gov/pubmed/7437288
_version_ 1782136324162060288
author van Bogaert, L. J.
de Muylder, C.
Maldague, P.
Maisin, H.
author_facet van Bogaert, L. J.
de Muylder, C.
Maldague, P.
Maisin, H.
author_sort van Bogaert, L. J.
collection PubMed
description The mean nuclear diameter of 100 breast cancers was measured on tissue sections, to evaluate its importance for early prognosis. The cases were subdivided into 3 subgroups: small (25.5% of cases), medium (63.3%) and large (11.2%) nuclei. Early recurrence and mortality rates were investigated in each of the categories. Increasing nuclear size was shown to be related to mortality from metastatic disease. However, large-nucleus tumours had an inverse relationship with lymphnode involvement and possibly with recurrence rate. Hence, in our material nuclear size as a sole criterion was not a good indicator of the early behaviour of operable breast cancer.
format Text
id pubmed-2010448
institution National Center for Biotechnology Information
language English
publishDate 1980
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-20104482009-09-10 Prognostic implications of mean nuclear diameter in breast cancer. van Bogaert, L. J. de Muylder, C. Maldague, P. Maisin, H. Br J Cancer Research Article The mean nuclear diameter of 100 breast cancers was measured on tissue sections, to evaluate its importance for early prognosis. The cases were subdivided into 3 subgroups: small (25.5% of cases), medium (63.3%) and large (11.2%) nuclei. Early recurrence and mortality rates were investigated in each of the categories. Increasing nuclear size was shown to be related to mortality from metastatic disease. However, large-nucleus tumours had an inverse relationship with lymphnode involvement and possibly with recurrence rate. Hence, in our material nuclear size as a sole criterion was not a good indicator of the early behaviour of operable breast cancer. Nature Publishing Group 1980-10 /pmc/articles/PMC2010448/ /pubmed/7437288 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
van Bogaert, L. J.
de Muylder, C.
Maldague, P.
Maisin, H.
Prognostic implications of mean nuclear diameter in breast cancer.
title Prognostic implications of mean nuclear diameter in breast cancer.
title_full Prognostic implications of mean nuclear diameter in breast cancer.
title_fullStr Prognostic implications of mean nuclear diameter in breast cancer.
title_full_unstemmed Prognostic implications of mean nuclear diameter in breast cancer.
title_short Prognostic implications of mean nuclear diameter in breast cancer.
title_sort prognostic implications of mean nuclear diameter in breast cancer.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010448/
https://www.ncbi.nlm.nih.gov/pubmed/7437288
work_keys_str_mv AT vanbogaertlj prognosticimplicationsofmeannucleardiameterinbreastcancer
AT demuylderc prognosticimplicationsofmeannucleardiameterinbreastcancer
AT maldaguep prognosticimplicationsofmeannucleardiameterinbreastcancer
AT maisinh prognosticimplicationsofmeannucleardiameterinbreastcancer

Ejemplares similares