Glycosaminoglycan content and synthesis in gastric carcinoma.

The glycosaminoglycan (GAG) content of stomach carcinoma tissue was compared with that of non-neoplastic mucosa. GAG synthesis was also studied, by an analysis of 35S-labelled material after incubation of tissue segments in medium containing 35SO4. No significant difference was found between the amo...

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Autores principales: Sobue, M., Takeuchi, J., Miura, K., Kawase, K., Mizuno, F., Sato, E.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1980
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010460/
https://www.ncbi.nlm.nih.gov/pubmed/6448616
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author Sobue, M.
Takeuchi, J.
Miura, K.
Kawase, K.
Mizuno, F.
Sato, E.
author_facet Sobue, M.
Takeuchi, J.
Miura, K.
Kawase, K.
Mizuno, F.
Sato, E.
author_sort Sobue, M.
collection PubMed
description The glycosaminoglycan (GAG) content of stomach carcinoma tissue was compared with that of non-neoplastic mucosa. GAG synthesis was also studied, by an analysis of 35S-labelled material after incubation of tissue segments in medium containing 35SO4. No significant difference was found between the amount of GAG and its components in the medullary carcinoma tissue and in non-neoplastic mucosa, but GAG synthesis of the carcinoma tissue was at a much higher rate than that of the non-neoplastic mucosa. In the autoradiograph, high 35S uptake in the carcinoma cells was observed. The GAG content of the scirrhous-carcinoma tissue was about twice that of medullary carcinoma. IMAGES:
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spelling pubmed-20104602009-09-10 Glycosaminoglycan content and synthesis in gastric carcinoma. Sobue, M. Takeuchi, J. Miura, K. Kawase, K. Mizuno, F. Sato, E. Br J Cancer Research Article The glycosaminoglycan (GAG) content of stomach carcinoma tissue was compared with that of non-neoplastic mucosa. GAG synthesis was also studied, by an analysis of 35S-labelled material after incubation of tissue segments in medium containing 35SO4. No significant difference was found between the amount of GAG and its components in the medullary carcinoma tissue and in non-neoplastic mucosa, but GAG synthesis of the carcinoma tissue was at a much higher rate than that of the non-neoplastic mucosa. In the autoradiograph, high 35S uptake in the carcinoma cells was observed. The GAG content of the scirrhous-carcinoma tissue was about twice that of medullary carcinoma. IMAGES: Nature Publishing Group 1980-07 /pmc/articles/PMC2010460/ /pubmed/6448616 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Sobue, M.
Takeuchi, J.
Miura, K.
Kawase, K.
Mizuno, F.
Sato, E.
Glycosaminoglycan content and synthesis in gastric carcinoma.
title Glycosaminoglycan content and synthesis in gastric carcinoma.
title_full Glycosaminoglycan content and synthesis in gastric carcinoma.
title_fullStr Glycosaminoglycan content and synthesis in gastric carcinoma.
title_full_unstemmed Glycosaminoglycan content and synthesis in gastric carcinoma.
title_short Glycosaminoglycan content and synthesis in gastric carcinoma.
title_sort glycosaminoglycan content and synthesis in gastric carcinoma.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010460/
https://www.ncbi.nlm.nih.gov/pubmed/6448616
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AT kawasek glycosaminoglycancontentandsynthesisingastriccarcinoma
AT mizunof glycosaminoglycancontentandsynthesisingastriccarcinoma
AT satoe glycosaminoglycancontentandsynthesisingastriccarcinoma

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