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Somatic-cell hybrids producing antibodies against CEA.
Monoclonal antibodies to carcinoembryonic antigen (CEA) promise improved specificity for the measurement of this widely expressed human cancer antigen. A mouse monoclonal antibody binds weakly to CEA in perchloric acid extracts of tumour but strongly to CEA similarly isolated from serum, and its spe...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1981
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010494/ https://www.ncbi.nlm.nih.gov/pubmed/7459230 |
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author | Rogers, G. T. Rawlins, G. A. Bagshawe, K. D. |
author_facet | Rogers, G. T. Rawlins, G. A. Bagshawe, K. D. |
author_sort | Rogers, G. T. |
collection | PubMed |
description | Monoclonal antibodies to carcinoembryonic antigen (CEA) promise improved specificity for the measurement of this widely expressed human cancer antigen. A mouse monoclonal antibody binds weakly to CEA in perchloric acid extracts of tumour but strongly to CEA similarly isolated from serum, and its spectrum of cancer detection differs from conventional antisera. |
format | Text |
id | pubmed-2010494 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1981 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20104942009-09-10 Somatic-cell hybrids producing antibodies against CEA. Rogers, G. T. Rawlins, G. A. Bagshawe, K. D. Br J Cancer Research Article Monoclonal antibodies to carcinoembryonic antigen (CEA) promise improved specificity for the measurement of this widely expressed human cancer antigen. A mouse monoclonal antibody binds weakly to CEA in perchloric acid extracts of tumour but strongly to CEA similarly isolated from serum, and its spectrum of cancer detection differs from conventional antisera. Nature Publishing Group 1981-01 /pmc/articles/PMC2010494/ /pubmed/7459230 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Rogers, G. T. Rawlins, G. A. Bagshawe, K. D. Somatic-cell hybrids producing antibodies against CEA. |
title | Somatic-cell hybrids producing antibodies against CEA. |
title_full | Somatic-cell hybrids producing antibodies against CEA. |
title_fullStr | Somatic-cell hybrids producing antibodies against CEA. |
title_full_unstemmed | Somatic-cell hybrids producing antibodies against CEA. |
title_short | Somatic-cell hybrids producing antibodies against CEA. |
title_sort | somatic-cell hybrids producing antibodies against cea. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010494/ https://www.ncbi.nlm.nih.gov/pubmed/7459230 |
work_keys_str_mv | AT rogersgt somaticcellhybridsproducingantibodiesagainstcea AT rawlinsga somaticcellhybridsproducingantibodiesagainstcea AT bagshawekd somaticcellhybridsproducingantibodiesagainstcea |