Lack of prognostic value of the thymidine-labelling index in adult acute leukaemia.

A study has been made of the thymidine labelling index (TLI) of marrow blast cells in 201 adults with untreated acute leukaemia. There was no significant difference between the TLI in 172 patients with acute myeloblastic leukaemia and 29 patients with acute lymphoblastic leukaemia. The TLI did not c...

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Autores principales: Sewell, R. L., Lister, T. A., Johnson, S. A., Crowther, D.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1981
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010651/
https://www.ncbi.nlm.nih.gov/pubmed/6942872
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author Sewell, R. L.
Lister, T. A.
Johnson, S. A.
Crowther, D.
author_facet Sewell, R. L.
Lister, T. A.
Johnson, S. A.
Crowther, D.
author_sort Sewell, R. L.
collection PubMed
description A study has been made of the thymidine labelling index (TLI) of marrow blast cells in 201 adults with untreated acute leukaemia. There was no significant difference between the TLI in 172 patients with acute myeloblastic leukaemia and 29 patients with acute lymphoblastic leukaemia. The TLI did not correlate with the age, sex, peripheral-blood or marrow blast-cell count, or the platelet count at presentation. In neither acute myeloblastic leukaemia nor acute lymphoblastic leukaemia was there any correlation between the TLI and the response to the initial therapy, the duration of the first complete remission or survival.
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spelling pubmed-20106512009-09-10 Lack of prognostic value of the thymidine-labelling index in adult acute leukaemia. Sewell, R. L. Lister, T. A. Johnson, S. A. Crowther, D. Br J Cancer Research Article A study has been made of the thymidine labelling index (TLI) of marrow blast cells in 201 adults with untreated acute leukaemia. There was no significant difference between the TLI in 172 patients with acute myeloblastic leukaemia and 29 patients with acute lymphoblastic leukaemia. The TLI did not correlate with the age, sex, peripheral-blood or marrow blast-cell count, or the platelet count at presentation. In neither acute myeloblastic leukaemia nor acute lymphoblastic leukaemia was there any correlation between the TLI and the response to the initial therapy, the duration of the first complete remission or survival. Nature Publishing Group 1981-07 /pmc/articles/PMC2010651/ /pubmed/6942872 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Sewell, R. L.
Lister, T. A.
Johnson, S. A.
Crowther, D.
Lack of prognostic value of the thymidine-labelling index in adult acute leukaemia.
title Lack of prognostic value of the thymidine-labelling index in adult acute leukaemia.
title_full Lack of prognostic value of the thymidine-labelling index in adult acute leukaemia.
title_fullStr Lack of prognostic value of the thymidine-labelling index in adult acute leukaemia.
title_full_unstemmed Lack of prognostic value of the thymidine-labelling index in adult acute leukaemia.
title_short Lack of prognostic value of the thymidine-labelling index in adult acute leukaemia.
title_sort lack of prognostic value of the thymidine-labelling index in adult acute leukaemia.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010651/
https://www.ncbi.nlm.nih.gov/pubmed/6942872
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AT johnsonsa lackofprognosticvalueofthethymidinelabellingindexinadultacuteleukaemia
AT crowtherd lackofprognosticvalueofthethymidinelabellingindexinadultacuteleukaemia

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