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Localization of human breast-carcinoma xenografts using antibodies to carcinoembryonic antigen.
Affinity-purified antibodies to carcinoembryonic antigen (CEA) have been injected into immune-suppressed mice bearing xenografts of human breast tumours. It has been shown that the antibodies localized in the tumours but not in normal tissues. The degree of tumour localization correlates with the am...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1981
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010670/ https://www.ncbi.nlm.nih.gov/pubmed/7248144 |
| _version_ | 1782136370737709056 |
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| author | Moshakis, V. Bailey, M. J. Ormerod, M. G. Westwood, J. H. Neville, A. M. |
| author_facet | Moshakis, V. Bailey, M. J. Ormerod, M. G. Westwood, J. H. Neville, A. M. |
| author_sort | Moshakis, V. |
| collection | PubMed |
| description | Affinity-purified antibodies to carcinoembryonic antigen (CEA) have been injected into immune-suppressed mice bearing xenografts of human breast tumours. It has been shown that the antibodies localized in the tumours but not in normal tissues. The degree of tumour localization correlates with the amount of tumour CEA, and is unaffected by levels of circulating CEA or CEA/anti-CEA immune complexes. |
| format | Text |
| id | pubmed-2010670 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 1981 |
| publisher | Nature Publishing Group |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-20106702009-09-10 Localization of human breast-carcinoma xenografts using antibodies to carcinoembryonic antigen. Moshakis, V. Bailey, M. J. Ormerod, M. G. Westwood, J. H. Neville, A. M. Br J Cancer Research Article Affinity-purified antibodies to carcinoembryonic antigen (CEA) have been injected into immune-suppressed mice bearing xenografts of human breast tumours. It has been shown that the antibodies localized in the tumours but not in normal tissues. The degree of tumour localization correlates with the amount of tumour CEA, and is unaffected by levels of circulating CEA or CEA/anti-CEA immune complexes. Nature Publishing Group 1981-05 /pmc/articles/PMC2010670/ /pubmed/7248144 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
| spellingShingle | Research Article Moshakis, V. Bailey, M. J. Ormerod, M. G. Westwood, J. H. Neville, A. M. Localization of human breast-carcinoma xenografts using antibodies to carcinoembryonic antigen. |
| title | Localization of human breast-carcinoma xenografts using antibodies to carcinoembryonic antigen. |
| title_full | Localization of human breast-carcinoma xenografts using antibodies to carcinoembryonic antigen. |
| title_fullStr | Localization of human breast-carcinoma xenografts using antibodies to carcinoembryonic antigen. |
| title_full_unstemmed | Localization of human breast-carcinoma xenografts using antibodies to carcinoembryonic antigen. |
| title_short | Localization of human breast-carcinoma xenografts using antibodies to carcinoembryonic antigen. |
| title_sort | localization of human breast-carcinoma xenografts using antibodies to carcinoembryonic antigen. |
| topic | Research Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010670/ https://www.ncbi.nlm.nih.gov/pubmed/7248144 |
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