Plasma prostaglandins in mucositis due to radiotherapy and chemotherapy for head and neck cancer.

Patients with head and neck cancer were treated with synchronous radiotherapy and chemotherapy (vincristine, bleomycin and methotrexate). Before treatment, mucositis was absent and low amounts of prostaglandin-like material were extracted from peripheral plasma. As treatment proceeded mucositis occu...

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Detalles Bibliográficos
Autores principales: Tanner, N. S., Stamford, I. F., Bennett, A.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1981
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010698/
https://www.ncbi.nlm.nih.gov/pubmed/7248158
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author Tanner, N. S.
Stamford, I. F.
Bennett, A.
author_facet Tanner, N. S.
Stamford, I. F.
Bennett, A.
author_sort Tanner, N. S.
collection PubMed
description Patients with head and neck cancer were treated with synchronous radiotherapy and chemotherapy (vincristine, bleomycin and methotrexate). Before treatment, mucositis was absent and low amounts of prostaglandin-like material were extracted from peripheral plasma. As treatment proceeded mucositis occurred, and its degree correlated with the amount of prostaglandin-like material extracted from the plasma. Some patients were given moderate doses of drugs which inhibit prostaglandin synthesis, but mucositis still occurred.
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spelling pubmed-20106982009-09-10 Plasma prostaglandins in mucositis due to radiotherapy and chemotherapy for head and neck cancer. Tanner, N. S. Stamford, I. F. Bennett, A. Br J Cancer Research Article Patients with head and neck cancer were treated with synchronous radiotherapy and chemotherapy (vincristine, bleomycin and methotrexate). Before treatment, mucositis was absent and low amounts of prostaglandin-like material were extracted from peripheral plasma. As treatment proceeded mucositis occurred, and its degree correlated with the amount of prostaglandin-like material extracted from the plasma. Some patients were given moderate doses of drugs which inhibit prostaglandin synthesis, but mucositis still occurred. Nature Publishing Group 1981-06 /pmc/articles/PMC2010698/ /pubmed/7248158 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Tanner, N. S.
Stamford, I. F.
Bennett, A.
Plasma prostaglandins in mucositis due to radiotherapy and chemotherapy for head and neck cancer.
title Plasma prostaglandins in mucositis due to radiotherapy and chemotherapy for head and neck cancer.
title_full Plasma prostaglandins in mucositis due to radiotherapy and chemotherapy for head and neck cancer.
title_fullStr Plasma prostaglandins in mucositis due to radiotherapy and chemotherapy for head and neck cancer.
title_full_unstemmed Plasma prostaglandins in mucositis due to radiotherapy and chemotherapy for head and neck cancer.
title_short Plasma prostaglandins in mucositis due to radiotherapy and chemotherapy for head and neck cancer.
title_sort plasma prostaglandins in mucositis due to radiotherapy and chemotherapy for head and neck cancer.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010698/
https://www.ncbi.nlm.nih.gov/pubmed/7248158
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AT stamfordif plasmaprostaglandinsinmucositisduetoradiotherapyandchemotherapyforheadandneckcancer
AT bennetta plasmaprostaglandinsinmucositisduetoradiotherapyandchemotherapyforheadandneckcancer

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