Lymphocytes infiltrating human breast cancers lack K-cell activity and show low levels of NK-cell activity.

Lymphocytes infiltrating human primary mammary carcinomas lack ADCC and show low levels of natural cytotoxicity. The peripheral blood lymphocytes, however, show a variable but prominent level of cytotoxicity. Lymphocyte preparations from breast tumours, when mixed with autologous blood lymphocytes,...

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Detalles Bibliográficos
Autores principales: Eremin, O., Coombs, R. R., Ashby, J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1981
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010737/
https://www.ncbi.nlm.nih.gov/pubmed/6268135
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author Eremin, O.
Coombs, R. R.
Ashby, J.
author_facet Eremin, O.
Coombs, R. R.
Ashby, J.
author_sort Eremin, O.
collection PubMed
description Lymphocytes infiltrating human primary mammary carcinomas lack ADCC and show low levels of natural cytotoxicity. The peripheral blood lymphocytes, however, show a variable but prominent level of cytotoxicity. Lymphocyte preparations from breast tumours, when mixed with autologous blood lymphocytes, significantly suppress their prominent killer- (K- and NK-) cell activities.
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spelling pubmed-20107372009-09-10 Lymphocytes infiltrating human breast cancers lack K-cell activity and show low levels of NK-cell activity. Eremin, O. Coombs, R. R. Ashby, J. Br J Cancer Research Article Lymphocytes infiltrating human primary mammary carcinomas lack ADCC and show low levels of natural cytotoxicity. The peripheral blood lymphocytes, however, show a variable but prominent level of cytotoxicity. Lymphocyte preparations from breast tumours, when mixed with autologous blood lymphocytes, significantly suppress their prominent killer- (K- and NK-) cell activities. Nature Publishing Group 1981-08 /pmc/articles/PMC2010737/ /pubmed/6268135 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Eremin, O.
Coombs, R. R.
Ashby, J.
Lymphocytes infiltrating human breast cancers lack K-cell activity and show low levels of NK-cell activity.
title Lymphocytes infiltrating human breast cancers lack K-cell activity and show low levels of NK-cell activity.
title_full Lymphocytes infiltrating human breast cancers lack K-cell activity and show low levels of NK-cell activity.
title_fullStr Lymphocytes infiltrating human breast cancers lack K-cell activity and show low levels of NK-cell activity.
title_full_unstemmed Lymphocytes infiltrating human breast cancers lack K-cell activity and show low levels of NK-cell activity.
title_short Lymphocytes infiltrating human breast cancers lack K-cell activity and show low levels of NK-cell activity.
title_sort lymphocytes infiltrating human breast cancers lack k-cell activity and show low levels of nk-cell activity.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010737/
https://www.ncbi.nlm.nih.gov/pubmed/6268135
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AT ashbyj lymphocytesinfiltratinghumanbreastcancerslackkcellactivityandshowlowlevelsofnkcellactivity

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