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Failure of specific active immunotherapy in lung cancer.
A randomized trial comparing routine follow-up with a treatment regimen aimed at increasing specific anti-tumour immunity has been carried out in 95 patients after total surgical excision of lung cancer (not small-cell). Treatment consisted of inoculation with an autologous irradiated suspension of...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1981
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010816/ https://www.ncbi.nlm.nih.gov/pubmed/7028069 |
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author | Souter, R. G. Gill, P. G. Gunning, A. J. Morris, P. J. |
author_facet | Souter, R. G. Gill, P. G. Gunning, A. J. Morris, P. J. |
author_sort | Souter, R. G. |
collection | PubMed |
description | A randomized trial comparing routine follow-up with a treatment regimen aimed at increasing specific anti-tumour immunity has been carried out in 95 patients after total surgical excision of lung cancer (not small-cell). Treatment consisted of inoculation with an autologous irradiated suspension of tumour cells combined with a small dose of C. parvum given intradermally during convalescence. Although treatment was associated with virtually no side effects, there has been no apparent benefit and input to the trial has now stopped. |
format | Text |
id | pubmed-2010816 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1981 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-20108162009-09-10 Failure of specific active immunotherapy in lung cancer. Souter, R. G. Gill, P. G. Gunning, A. J. Morris, P. J. Br J Cancer Research Article A randomized trial comparing routine follow-up with a treatment regimen aimed at increasing specific anti-tumour immunity has been carried out in 95 patients after total surgical excision of lung cancer (not small-cell). Treatment consisted of inoculation with an autologous irradiated suspension of tumour cells combined with a small dose of C. parvum given intradermally during convalescence. Although treatment was associated with virtually no side effects, there has been no apparent benefit and input to the trial has now stopped. Nature Publishing Group 1981-10 /pmc/articles/PMC2010816/ /pubmed/7028069 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Souter, R. G. Gill, P. G. Gunning, A. J. Morris, P. J. Failure of specific active immunotherapy in lung cancer. |
title | Failure of specific active immunotherapy in lung cancer. |
title_full | Failure of specific active immunotherapy in lung cancer. |
title_fullStr | Failure of specific active immunotherapy in lung cancer. |
title_full_unstemmed | Failure of specific active immunotherapy in lung cancer. |
title_short | Failure of specific active immunotherapy in lung cancer. |
title_sort | failure of specific active immunotherapy in lung cancer. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010816/ https://www.ncbi.nlm.nih.gov/pubmed/7028069 |
work_keys_str_mv | AT souterrg failureofspecificactiveimmunotherapyinlungcancer AT gillpg failureofspecificactiveimmunotherapyinlungcancer AT gunningaj failureofspecificactiveimmunotherapyinlungcancer AT morrispj failureofspecificactiveimmunotherapyinlungcancer |