Cargando…

Response of murine tumours to combinations of CCNU with misonidazole and other radiation sensitizers.

The effect of combinations of the conventional chemotherapeutic agent 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and nitroimidazole radiation sensitizers was evaluated in female C3H mice. Tumour response to single-agent or combination therapy was assessed in a tumour growth-delay assay. In...

Descripción completa

Detalles Bibliográficos
Autor principal:	Siemann, D. W.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1982
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010911/ https://www.ncbi.nlm.nih.gov/pubmed/6460517

Ejemplares similares

In vivo combination of misonidazole and the chemotherapeutic agent CCNU.
por: Siemann, D. W.
Publicado: (1981)

Chemosensitization by misonidazole in CCNU-treated spheroids and tumours.
por: Durand, R. E., et al.
Publicado: (1987)

Chemopotentiation of CCNU metabolites by misonidazole.
por: Mulcahy, R. T.
Publicado: (1985)

Enhancement of CCNU cytotoxicity by misonidazole: possible therapeutic gain.
por: Hirst, D. G., et al.
Publicado: (1982)

Misonidazole protects mouse tumour and normal tissues from the toxicity of oral CCNU.
por: Lee, F. Y., et al.
Publicado: (1985)

Modification of CCNU pharmacokinetics by misonidazole--a major mechanism of chemosensitization in mice.
por: Lee, F. Y., et al.
Publicado: (1983)

Misonidazole and CCNU: further evidence for a pharmacokinetic mechanism of chemosensitization and therapeutic gain.
por: Lee, F. Y., et al.
Publicado: (1984)

Effect of misonidazole or metronidazole pretreatment on the response of the RIF-1 mouse sarcoma to melphalan, cyclophosphamide, chlorambucil and CCNU.
por: Twentyman, P., et al.
Publicado: (1982)

The quantitative response of human tumours to radiation and misonidazole.
por: Ash, D. V., et al.
Publicado: (1979)

Effects of nandrolone decanoate on the toxicity and anti-tumour action of CCNU and FU in murine tumours.
por: Bibby, M. C., et al.
Publicado: (1981)

Response of two mouse tumours to hyperthermia with CCNU or melphalan.
por: Joiner, M. C., et al.
Publicado: (1982)

In vitro potentiation of BCNU activity in rat brain tumour cells pretreated with misonidazole.
por: Siemann, D. W., et al.
Publicado: (1984)

Misonidazole reduces blood flow in two experimental murine tumours.
por: Murray, J. C., et al.
Publicado: (1988)

Nitrosourea-misonidazole combination chemotherapy: effect on KHT sarcomas, marrow stem cells and gut.
por: Mulcahy, R. T., et al.
Publicado: (1982)

Influence of misonidazole on the incidence of radiation-induced intestinal tumours in mice.
por: Rostom, A. Y., et al.
Publicado: (1978)

Hypoxic cells and in situ chemopotentiation of the nitrosoureas by misonidazole.
por: Wheeler, K. T., et al.
Publicado: (1984)

The penetration of misonidazole into spontaneous canine tumours.
por: White, R. A., et al.
Publicado: (1979)

Enhancing effect of misonidazole on the response of the RIF-1 tumour to cyclophosphamide.
por: Law, M. P., et al.
Publicado: (1981)

Distribution of misonidazole in human tumours and normal tissues.
por: Ash, D. V., et al.
Publicado: (1979)

Is tumour radiosensitization by misonidazole a general phenomenon?
por: Denekamp, J., et al.
Publicado: (1980)

The effect of misonidazole combined with WR2721 on tumour response and leucopenia due to cyclophosphamide or melphalan.
por: McNally, N. J.
Publicado: (1982)

Modification of tumour and host response to cyclophosphamide by misonidazole and by WR 2721.
por: Twentyman, P. R.
Publicado: (1981)

The effects of melphalan and misonidazole on the vasculature of a murine sarcoma.
por: Murray, J. C., et al.
Publicado: (1987)

Structure/activity relationships for the enhancement by electron-affinic drugs of the anti-tumour effect of CCNU.
por: Workman, P., et al.
Publicado: (1982)

Effect of misonidazole on radiation injury to mouse spinal cord.
por: Travis, E. L., et al.
Publicado: (1982)

Cisplatin and CCNU synergism in spheroid cell subpopulations.
por: Durand, R. E.
Publicado: (1990)

Effects on tumour microcirculation in mice of misonidazole and tumour necrosis factor plus hyperthermia.
por: Fujimoto, S., et al.
Publicado: (1992)

The binding of 14C labelled 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) to macromolecules of sensitive and resistant tumours.
por: Connors, T. A., et al.
Publicado: (1974)

Identification of a subpopulation of MeCCNU resistant cells in previously untreated Lewis lung tumours.
por: Stephens, T. C., et al.
Publicado: (1984)

Emergence of nitrosourea resistant sublines of Lewis lung tumour following MeCCNU treatment in vivo.
por: Stephens, T. C., et al.
Publicado: (1986)

Effect of clinical levels of misonidazole on the response of tumour and normal tissues in the mouse to alkylating agents.
por: Brown, J. M., et al.
Publicado: (1982)

Interaction of misonidazole and WR-2721--II. Modification of tumour radiosensitization.
por: Rojas, A., et al.
Publicado: (1983)

In vitro metabolism of misonidazole.
por: Josephy, P. D., et al.
Publicado: (1981)

The effect of hypobaric hypoxia on misonidazole binding in normal and tumour-bearing mice.
por: MacManus, M. P., et al.
Publicado: (1989)

Bleomycin and misonidazole cytotoxicity.
por: Korbelik, M., et al.
Publicado: (1985)

Procarbazine, CCNU, and Vincristine Chemotherapy in Gliomatosis Cerebri
por: Lee, Hyun Gon, et al.
Publicado: (2014)

Radiation sensitization and chemopotentiation: RSU 1069, a compound more efficient than misonidazole in vitro and in vivo.
por: Adams, G. E., et al.
Publicado: (1984)

Oncogenic transformation in vitro by the hypoxic cell sensitizer misonidazole.
por: Miller, R. C., et al.
Publicado: (1978)

Does misonidazole enhance radiation injury to the central nervous system?
por: Field, S. B., et al.
Publicado: (1981)

Enhancement of melphalan-induced tumour cell killing by misonidazole: an interaction of competing mechanisms.
por: Horsman, M. R., et al.
Publicado: (1984)

Cannot write session to /tmp/vufind_sessions/sess_l9nfuv8tncee0en6qvgt2h49il