Effect of misonidazole or metronidazole pretreatment on the response of the RIF-1 mouse sarcoma to melphalan, cyclophosphamide, chlorambucil and CCNU.

The effect has been studied of adding either misonidazole (MISO) or metronidazole (METRO) to cytotoxic drug treatment of C3H mice bearing the RIF-1 sarcoma. The nitroimidazoles were injected 30 min before the cytotoxic drugs at a dose of 2 . 5 mmol/kg. Both clonogenic-cell survival and growth delay...

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Detalles Bibliográficos
Autores principales: Twentyman, P., Workman, P.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1982
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010916/
https://www.ncbi.nlm.nih.gov/pubmed/7073938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010916/
https://www.ncbi.nlm.nih.gov/pubmed/7073938

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