Plasma protein profiles and prognosis in gastric cancer.

In 104 patients with gastric cancer the serum proteins carcinoembryonic antigen (CEA), C-reactive protein (CRP), alpha 1-acid glycoprotein (AGP) (orosomucoid) and alpha 1-antichymotrypsin (ACT) were measured pre-operatively. The estimated median survival of patients with both raised CEA and ACT was...

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Autores principales: Rashid, S. A., O'Quigley, J., Axon, A. T., Cooper, E. H.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1982
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010918/
https://www.ncbi.nlm.nih.gov/pubmed/6896153
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author Rashid, S. A.
O'Quigley, J.
Axon, A. T.
Cooper, E. H.
author_facet Rashid, S. A.
O'Quigley, J.
Axon, A. T.
Cooper, E. H.
author_sort Rashid, S. A.
collection PubMed
description In 104 patients with gastric cancer the serum proteins carcinoembryonic antigen (CEA), C-reactive protein (CRP), alpha 1-acid glycoprotein (AGP) (orosomucoid) and alpha 1-antichymotrypsin (ACT) were measured pre-operatively. The estimated median survival of patients with both raised CEA and ACT was only 5 weeks in contrast to 64 weeks for those with both proteins normal. An intermediary group with one of these proteins raised and the other normal had an estimated median survival of 15 weeks. Similar results were obtained by considering a combination of CEA with either AGP or CRP. For these data the results were not explicable in terms of associations between survival time and patient's age, stage, operative procedure, histological classification or site of primary tumour.
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spelling pubmed-20109182009-09-10 Plasma protein profiles and prognosis in gastric cancer. Rashid, S. A. O'Quigley, J. Axon, A. T. Cooper, E. H. Br J Cancer Research Article In 104 patients with gastric cancer the serum proteins carcinoembryonic antigen (CEA), C-reactive protein (CRP), alpha 1-acid glycoprotein (AGP) (orosomucoid) and alpha 1-antichymotrypsin (ACT) were measured pre-operatively. The estimated median survival of patients with both raised CEA and ACT was only 5 weeks in contrast to 64 weeks for those with both proteins normal. An intermediary group with one of these proteins raised and the other normal had an estimated median survival of 15 weeks. Similar results were obtained by considering a combination of CEA with either AGP or CRP. For these data the results were not explicable in terms of associations between survival time and patient's age, stage, operative procedure, histological classification or site of primary tumour. Nature Publishing Group 1982-03 /pmc/articles/PMC2010918/ /pubmed/6896153 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Rashid, S. A.
O'Quigley, J.
Axon, A. T.
Cooper, E. H.
Plasma protein profiles and prognosis in gastric cancer.
title Plasma protein profiles and prognosis in gastric cancer.
title_full Plasma protein profiles and prognosis in gastric cancer.
title_fullStr Plasma protein profiles and prognosis in gastric cancer.
title_full_unstemmed Plasma protein profiles and prognosis in gastric cancer.
title_short Plasma protein profiles and prognosis in gastric cancer.
title_sort plasma protein profiles and prognosis in gastric cancer.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010918/
https://www.ncbi.nlm.nih.gov/pubmed/6896153
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AT oquigleyj plasmaproteinprofilesandprognosisingastriccancer
AT axonat plasmaproteinprofilesandprognosisingastriccancer
AT coopereh plasmaproteinprofilesandprognosisingastriccancer

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