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Modulation of the toxicity and antitumour activity of alkylating drugs by steroids.

The steroids prednisolone and progesterone significantly altered the therapeutic indices of the alkylating agents, nitrogen mustard, melphalan, cyclophosphamide, phenyl acetic mustard and chlorambucil. For nitrogen mustard, chlorambucil and phenyl acetic mustard, prednisolone reduced host toxicity i...

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Detalles Bibliográficos
Autores principales: Shepherd, R., Harrap, K. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1982
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010934/
https://www.ncbi.nlm.nih.gov/pubmed/7073935