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Spontaneously metastasizing variants derived from MNU-induced rat mammary tumour.
N-methyl-N-nitrosourea (MNU) given i.v. to female rats of inbred strains induces mammary adenocarcinomas which are hormone-sensitive but do not spontaneously metastasize (Williams et al., 1981). Tissue culture and selection techniques have been used to derive metastasizing tumours from a mammary tum...
Autores principales: | Williams, J. C., Gusterson, B. A., Coombes, R. C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1982
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2010985/ https://www.ncbi.nlm.nih.gov/pubmed/7073949 |
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